Gut microbial molecules in behavioural and neurodegenerative conditions

BD Needham, R Kaddurah-Daouk… - Nature Reviews …, 2020‏ - nature.com
Mounting evidence suggests that the gut microbiome impacts brain development and
function. Gut–brain connections may be mediated by an assortment of microbial molecules …

Genome-resolved metagenomics: a game changer for microbiome medicine

N Kim, J Ma, W Kim, J Kim, P Belenky… - Experimental & Molecular …, 2024‏ - nature.com
Recent substantial evidence implicating commensal bacteria in human diseases has given
rise to a new domain in biomedical research: microbiome medicine. This emerging field …

[HTML][HTML] Gut microbiota remodeling improves natural aging-related disorders through Akkermansia muciniphila and its derived acetic acid

J Ma, Z Liu, X Gao, Y Bao, Y Hong, X He, W Zhu… - Pharmacological …, 2023‏ - Elsevier
Accumulating evidence indicates gut microbiota contributes to aging-related disorders.
However, the exact mechanism underlying gut dysbiosis-related pathophysiological …

Guide to metabolomics analysis: a bioinformatics workflow

Y Chen, EM Li, LY Xu - Metabolites, 2022‏ - mdpi.com
Metabolomics is an emerging field that quantifies numerous metabolites systematically. The
key purpose of metabolomics is to identify the metabolites corresponding to each biological …

High-coverage metabolomics uncovers microbiota-driven biochemical landscape of interorgan transport and gut-brain communication in mice

Y Lai, CW Liu, Y Yang, YC Hsiao, H Ru, K Lu - Nature communications, 2021‏ - nature.com
The mammalian gut harbors a complex and dynamic microbial ecosystem: the microbiota.
While emerging studies support that microbiota regulates brain function with a few molecular …

Desulfovibrio in the Gut: The Enemy within?

SB Singh, A Carroll-Portillo, HC Lin - Microorganisms, 2023‏ - mdpi.com
Desulfovibrio (DSV) are sulfate-reducing bacteria (SRB) that are ubiquitously present in the
environment and as resident commensal bacteria within the human gastrointestinal tract …

Short chain fatty acids-producing and mucin-degrading intestinal bacteria predict the progression of early Parkinson's disease

H Nishiwaki, M Ito, T Hamaguchi, T Maeda… - npj Parkinson's …, 2022‏ - nature.com
To elucidate the relevance of gut dysbiosis in Parkinson's disease (PD) in disease
progression, we made random forest models to predict the progression of PD in two years by …

[PDF][PDF] Maternal inflammation and its ramifications on fetal neurodevelopment

HK Kwon, GB Choi, JR Huh - Trends in immunology, 2022‏ - cell.com
Exposure to heightened inflammation in pregnancy caused by infections or other
inflammatory insults has been associated with the onset of neurodevelopmental and …

Bile acid signaling in the regulation of whole body metabolic and immunological homeostasis

W Jia, Y Li, KCP Cheung, X Zheng - Science China Life Sciences, 2024‏ - Springer
Bile acids (BAs) play a crucial role in nutrient absorption and act as key regulators of lipid
and glucose metabolism and immune homeostasis. Through the enterohepatic circulation …

Parkinson's disease-associated alterations of the gut microbiome predict disease-relevant changes in metabolic functions

F Baldini, J Hertel, E Sandt, CC Thinnes… - BMC biology, 2020‏ - Springer
Background Parkinson's disease (PD) is a systemic disease clinically defined by the
degeneration of dopaminergic neurons in the brain. While alterations in the gut microbiome …