Histotripsy: a method for mechanical tissue ablation with ultrasound

Z Xu, TD Khokhlova, CS Cho… - Annual Review of …, 2024 - annualreviews.org
Histotripsy is a relatively new therapeutic ultrasound technology to mechanically liquefy
tissue into subcellular debris using high-amplitude focused ultrasound pulses. In contrast to …

Effects of phase aberration on transabdominal focusing for a large aperture, low f-number histotripsy transducer

E Yeats, D Gupta, Z Xu, TL Hall - Physics in Medicine & Biology, 2022 - iopscience.iop.org
Objective. Soft tissue phase aberration may be particularly severe for histotripsy due to large
aperture and low f-number transducer geometries. This study investigated how phase …

Soft tissue aberration correction for histotripsy using acoustic emissions from cavitation cloud nucleation and collapse

E Yeats, N Lu, JR Sukovich, Z Xu, TL Hall - Ultrasound in medicine & …, 2023 - Elsevier
Objective Phase aberration from soft tissue limits the efficacy of histotripsy, a therapeutic
ultrasound technique based on acoustic cavitation. Previous work has shown that the …

Treatment envelope of transcranial histotripsy: challenges and strategies to maximize the treatment location profile

N Lu, EM Yeats, JR Sukovich, TL Hall… - Physics in Medicine …, 2024 - iopscience.iop.org
Abstract A 750 kHz, 360-element ultrasound array has been built for transcranial histotripsy
applications. This study aims to evaluate its performance to determine whether this array is …