Abstract Narcolepsy type 1 (NT1) is a chronic sleep disorder resulting from the loss of a
small population of hypothalamic neurons that produce wake-promoting hypocretin (HCRT; …

Narcolepsy is a chronic sleep disorder that has a typical onset in adolescence and is
characterized by excessive daytime sleepiness, which can have severe consequences for …

This article addresses the clinical presentation, diagnosis, pathophysiology and
management of narcolepsy type 1 and 2, with a focus on recent findings. A low level of …

Study objective To assess comorbidities in a community-based cohort of narcolepsy.
Methods A 2000–2014 community-based narcolepsy cohort was identified in Olmsted …

Narcolepsy type 1 is a life-long, severe, multifaceted disease often arising in childhood or
adolescence. Beyond the classical symptoms (excessive daytime sleepiness, cataplexy …

Idiopathic hypersomnia (IH) is a chronic neurologic disorder that manifests as pathologic
daytime sleepiness with or without prolonged sleep durations. Population-based estimates …

Abstract Purpose of Review After the connection between AS03-adjuvanted pandemic
H1N1 vaccine Pandemrix and narcolepsy was recognized in 2010, research on narcolepsy …

Narcolepsy is mainly associated with excessive daytime sleepiness, but the characteristic
feature is abnormal rapid eye movement (REM) sleep phenomena. REM sleep disturbances …

Idiopathic hypersomnia (IH) includes a clinical phenotype resembling narcolepsy (with
repeated, short restorative naps), and a phenotype with an excess of sleep, sleep …

Patients with narcolepsy live with a lifelong sleep-wake disorder, impairing their quality of
life, productivity, educational and employment outcomes. Clinicians are becoming aware …