Cryogenically cooled probes—a leap in NMR technology

H Kovacs, D Moskau, M Spraul - Progress in Nuclear Magnetic Resonance …, 2005 - Elsevier
During the 50 years of NMR, the technology has renewed itself again and again although
the basic physical principles remain the same. As technical advances and novel materials …

NMR studies of protein structure and dynamics

LE Kay - Journal of magnetic resonance, 2011 - Elsevier
Recent advances in solution NMR spectroscopy have significantly extended the spectrum of
problems that can now be addressed with this technology. In particular, studies of proteins …

Structure and mechanism of the M2 proton channel of influenza A virus

JR Schnell, JJ Chou - Nature, 2008 - nature.com
The integral membrane protein M2 of influenza virus forms pH-gated proton channels in the
viral lipid envelope. The low pH of an endosome activates the M2 channel before …

Solution structure of calcium-free calmodulin

H Kuboniwa, N Tjandra, S Grzesiek, H Ren… - Nature structural …, 1995 - nature.com
The three-dimensional structure of calmodulin in the absence of Ca2+ has been determined
by three-and four-dimensional heteronuclear NMR experiments, including ROE, isotope …

Solution structure of dengue virus capsid protein reveals another fold

L Ma, CT Jones, TD Groesch, RJ Kuhn… - Proceedings of the …, 2004 - pnas.org
Dengue virus is responsible for≈ 50–100 million infections, resulting in nearly 24,000
deaths annually. The capsid (C) protein of dengue virus is essential for specific …

Mutual synergistic folding in recruitment of CBP/p300 by p160 nuclear receptor coactivators

SJ Demarest, M Martinez-Yamout, J Chung, H Chen… - Nature, 2002 - nature.com
Nuclear hormone receptors are ligand-activated transcription factors that regulate the
expression of genes that are essential for development, reproduction and homeostasis. The …

The solution structure of an HMG-I (Y)–DNA complex defines a new architectural minor groove binding motif

JR Huth, CA Bewley, MS Nissen, JNS Evans… - Nature structural …, 1997 - nature.com
The solution structure of a complex between a truncated form of HMG-I (Y), consisting of the
second and third DNA binding domains (residues 51–90), and a DNA dodecamer …

NMR structure of a specific DNA complex of Zn-containing DNA binding domain of GATA-1

JG Omichinski, GM Clore, O Schaad, G Felsenfeld… - Science, 1993 - science.org
The three-dimensional solution structure of a complex between the DNA binding domain of
the chicken erythroid transcription factor GATA-1 and its cognate DNA site has been …

PD-L1 degradation is regulated by electrostatic membrane association of its cytoplasmic domain

M Wen, Y Cao, B Wu, T **ao, R Cao, Q Wang… - Nature …, 2021 - nature.com
The cytoplasmic domain of PD-L1 (PD-L1-CD) regulates PD-L1 degradation and stability
through various mechanism, making it an attractive target for blocking PD-L1-related cancer …

Weak alignment offers new NMR opportunities to study protein structure and dynamics

AD Bax - Protein Science, 2003 - Wiley Online Library
Protein solution nuclear magnetic resonance (NMR) can be conducted in a slightly
anisotropic environment, where the orientational distribution of the proteins is no longer …