LNCcation: lncRNA localization and function
Subcellular localization of RNAs has gained attention in recent years as a prevalent
phenomenon that influences numerous cellular processes. This is also evident for the large …
phenomenon that influences numerous cellular processes. This is also evident for the large …
Exploiting the biogenesis of extracellular vesicles for bioengineering and therapeutic cargo loading
J Rädler, D Gupta, A Zickler, SEL Andaloussi - Molecular Therapy, 2023 - cell.com
Extracellular vesicles (EVs) are gaining increasing attention for diagnostic and therapeutic
applications in various diseases. These natural nanoparticles benefit from favorable safety …
applications in various diseases. These natural nanoparticles benefit from favorable safety …
RNA delivery by extracellular vesicles in mammalian cells and its applications
The term 'extracellular vesicles' refers to a heterogeneous population of vesicular bodies of
cellular origin that derive either from the endosomal compartment (exosomes) or as a result …
cellular origin that derive either from the endosomal compartment (exosomes) or as a result …
Molecular Landscape of LncRNAs in Prostate Cancer: A focus on pathways and therapeutic targets for intervention
Background One of the most malignant tumors in men is prostate cancer that is still incurable
due to its heterogenous and progressive natures. Genetic and epigenetic changes play …
due to its heterogenous and progressive natures. Genetic and epigenetic changes play …
Regulation of microRNA function in animals
Since their serendipitous discovery in nematodes, microRNAs (miRNAs) have emerged as
key regulators of biological processes in animals. These small RNAs form complex networks …
key regulators of biological processes in animals. These small RNAs form complex networks …
RNA packaging into extracellular vesicles: An orchestra of RNA‐binding proteins?
Extracellular vesicles (EVs) are heterogeneous membranous particles released from the
cells through different biogenetic and secretory mechanisms. We now conceive EVs as …
cells through different biogenetic and secretory mechanisms. We now conceive EVs as …
Cytoplasmic functions of long noncoding RNAs
Long noncoding RNAs (lncRNAs) are transcripts longer than 200 nucleotides found
throughout the cell that lack protein‐coding function. Their functions are closely linked to …
throughout the cell that lack protein‐coding function. Their functions are closely linked to …
Emerging role of exosome-derived long non-coding RNAs in tumor microenvironment
Z Sun, S Yang, Q Zhou, G Wang, J Song, Z Li, Z Zhang… - Molecular cancer, 2018 - Springer
Exosomes are extracellular vesicles released by many cell types and have been attributed
for their roles in many diseases including cancer. Exosomes secreted by tumor cells and …
for their roles in many diseases including cancer. Exosomes secreted by tumor cells and …
Exosomes: from garbage bins to promising therapeutic targets
Intercellular communication via cell-released vesicles is a very important process for both
normal and tumor cells. Cell communication may involve exosomes, small vesicles of …
normal and tumor cells. Cell communication may involve exosomes, small vesicles of …
RNA in extracellular vesicles
Cells release a range of membrane‐enclosed extracellular vesicles (EVs) into the
environment. Among them, exosomes and microvesicles (collectively measuring 40–1000 …
environment. Among them, exosomes and microvesicles (collectively measuring 40–1000 …