Engineered living materials for sustainability

B An, Y Wang, Y Huang, X Wang, Y Liu, D Xun… - Chemical …, 2022 - ACS Publications
Recent advances in synthetic biology and materials science have given rise to a new form of
materials, namely engineered living materials (ELMs), which are composed of living matter …

Synthetic protein condensates for cellular and metabolic engineering

ZG Qian, SC Huang, XX **a - Nature chemical biology, 2022 - nature.com
Protein condensates are distinct structures assembled in living cells that concentrate
molecules via phase separation in a confined subcellular compartment. In the past decade …

Bioinspired hierarchical self‐assembled nanozyme for efficient antibacterial treatment

N Song, Y Yu, Y Zhang, Z Wang, Z Guo… - Advanced …, 2024 - Wiley Online Library
Along with the rapid development and ever‐deepening understanding of nanoscience and
nanotechnology, nanomaterials hold promise to mimic the highly evolved biological …

Determinants that enable disordered protein assembly into discrete condensed phases

RM Welles, KA Sojitra, MV Garabedian, B **a… - Nature Chemistry, 2024 - nature.com
Cells harbour numerous mesoscale membraneless compartments that house specific
biochemical processes and perform distinct cellular functions. These protein-and RNA-rich …

Synthesizing biomaterials in living organisms

X Zhang, J Wang, Y Zhang, Z Yang, J Gao… - Chemical Society …, 2023 - pubs.rsc.org
Living organisms fabricate biomacromolecules such as DNA, RNA, and proteins by the self-
assembly process. The research on the mechanism of biomacromolecule formation also …

Biomaterial-based platforms for tumour tissue engineering

R Curvello, V Kast, P Ordóñez-Morán, A Mata… - Nature Reviews …, 2023 - nature.com
Tissue engineering has produced innovative tools for cancer research. 3D cancer models
based on molecularly designed biomaterials aim to harness the dimensionality and …

[HTML][HTML] Biomineralization inspired 3D printed bioactive glass nanocomposite scaffolds orchestrate diabetic bone regeneration by remodeling micromilieu

Z Xu, X Qi, M Bao, T Zhou, J Shi, Z Xu, M Zhou… - Bioactive Materials, 2023 - Elsevier
Type II diabetes mellitus (TIIDM) remains a challenging clinical issue for both dentists and
orthopedists. By virtue of persistent hyperglycemia and altered host metabolism, the …

Using chemistry to recreate the complexity of the extracellular matrix: Guidelines for supramolecular hydrogel–cell interactions

L Rijns, MB Baker, PYW Dankers - Journal of the American …, 2024 - ACS Publications
Hydrogels have emerged as a promising class of extracellular matrix (ECM)-mimicking
materials in regenerative medicine. Here, we briefly describe current state-of-the-art of ECM …

Programmable synthetic receptors: the next-generation of cell and gene therapies

F Teng, T Cui, L Zhou, Q Gao, Q Zhou… - Signal Transduction and …, 2024 - nature.com
Cell and gene therapies hold tremendous promise for treating a range of difficult-to-treat
diseases. However, concerns over the safety and efficacy require to be further addressed in …

Spinal cord tissue engineering via covalent interaction between biomaterials and cells

W Liu, B Xu, S Zhao, S Han, R Quan, W Liu, C Ji… - Science …, 2023 - science.org
Noncovalent interactions between cells and environmental cues have been recognized as
fundamental physiological interactions that regulate cell behavior. However, the effects of …