Structural insights into three sesquiterpene synthases for the biosynthesis of tricyclic sesquiterpenes and chemical space expansion by structure-based mutagenesis

T Lou, A Li, H Xu, J Pan, B ** an energy supply-chain based on renewable biomass holds great potential to
build a low carbon society. High-energy-density (HED) jet fuel, featuring unique …

Requirements for terpene cyclizations inside the supramolecular resorcinarene capsule: bound water and its protonation determine the catalytic activity

S Merget, L Catti, GM Piccini… - Journal of the American …, 2020 - ACS Publications
The elucidation of the requirements for efficient catalysis within supramolecular host systems
is an important prerequisite for develo** novel supramolecular catalysts. The …

Four-step access to the sesquiterpene natural product presilphiperfolan-1β-ol and unnatural derivatives via supramolecular catalysis

LD Syntrivanis, I Némethová, D Schmid… - Journal of the …, 2020 - ACS Publications
Terpenes constitute one of the most structurally varied classes of natural products. A wide
range of these structures are produced in nature by type I terpene cyclase enzymes from …

Enantioselective access to tricyclic tetrahydropyran derivatives by a remote hydrogen bonding mediated intramolecular IEDHDA reaction

M **, C Tang, Y Li, S Yang, YT Yang, L Peng… - Nature …, 2021 - nature.com
Abstract Inverse-electron-demand-hetero-Diels-Alder reactions of alkenes with α, β-
unsaturated keto compounds allow rapid access to the tetrahydropyran ring found in …

Optimized iminium-catalysed 1, 4-reductions inside the resorcinarene capsule: achieving> 90% ee with proline as catalyst

D Sokolova, K Tiefenbacher - RSC advances, 2021 - pubs.rsc.org
In previous work, we demonstrated that iminium-catalysed 1, 4-reductions inside the
supramolecular resorcinarene capsule display increased enantioselectivities as compared …

Unlocking Oxetane Potential: Modular Synthetic Platform for the Concise Synthesis of Acyclic Oligo‐Isoprenoids and Terpenoids

K Albitz, S Tóth, D Csókás, T Soós - Angewandte Chemie, 2025 - Wiley Online Library
Terpenes occupy a unique place among the secondary metabolites due to their broad utility
and extraordinary structural diversity. Their synthesis via polyene cyclization, either …

Protection and Transformation of Natural Products within Aqueous Metal‐Organic Cages

S Cruz‐Nava… - European Journal of …, 2022 - Wiley Online Library
Natural products are central to the organic synthesis field and attract immense interest due
to their biological activity and wide industrial use. However, many suffer from poor aqueous …