ATP synthase

W Junge, N Nelson - Annual review of biochemistry, 2015 - annualreviews.org
Oxygenic photosynthesis is the principal converter of sunlight into chemical energy.
Cyanobacteria and plants provide aerobic life with oxygen, food, fuel, fibers, and platform …

[HTML][HTML] Filming biomolecular processes by high-speed atomic force microscopy

T Ando, T Uchihashi, S Scheuring - Chemical reviews, 2014 - ACS Publications
In the history of science and technology, researchers have always undertaken endeavors to
enhance the degree of “directness of measurement”. With “directness of measurement”, we …

Conformation space of a heterodimeric ABC exporter under turnover conditions

S Hofmann, D Januliene, AR Mehdipour, C Thomas… - Nature, 2019 - nature.com
Cryo-electron microscopy (cryo-EM) has the capacity to capture molecular machines in
action,–. ATP-binding cassette (ABC) exporters are highly dynamic membrane proteins that …

High-Speed Atomic Force Microscopy Reveals Rotary Catalysis of Rotorless F1-ATPase

T Uchihashi, R Iino, T Ando, H Noji - Science, 2011 - science.org
F1 is an adenosine triphosphate (ATP)–driven motor in which three torque-generating β
subunits in the α3β3 stator ring sequentially undergo conformational changes upon ATP …

The six steps of the complete F1-ATPase rotary catalytic cycle

M Sobti, H Ueno, H Noji, AG Stewart - Nature Communications, 2021 - nature.com
F1Fo ATP synthase interchanges phosphate transfer energy and proton motive force via a
rotary catalysis mechanism. Isolated F1-ATPase catalytic cores can hydrolyze ATP, passing …

Molecular mechanism on forcible ejection of ATPase inhibitory factor 1 from mitochondrial ATP synthase

R Kobayashi, H Ueno, K Okazaki, H Noji - Nature Communications, 2023 - nature.com
IF1 is a natural inhibitor protein for mitochondrial FoF1 ATP synthase that blocks catalysis
and rotation of the F1 by deeply inserting its N-terminal helices into F1. A unique feature of …

Rotation and structure of FoF1-ATP synthase

D Okuno, R Iino, H Noji - The Journal of Biochemistry, 2011 - academic.oup.com
Abstract F o F 1-ATP synthase is one of the most ubiquitous enzymes; it is found widely in
the biological world, including the plasma membrane of bacteria, inner membrane of …

A guide to magnetic tweezers and their applications

R Sarkar, VV Rybenkov - Frontiers in Physics, 2016 - frontiersin.org
Magnetic force spectroscopy is a rapidly develo** single molecule technique that has
found numerous applications at the interface of physics and biology. Since the invention of …

Thermodynamic efficiency and mechanochemical coupling of F1-ATPase

S Toyabe, T Watanabe-Nakayama… - Proceedings of the …, 2011 - National Acad Sciences
F1-ATPase is a nanosized biological energy transducer working as part of FoF1-ATP
synthase. Its rotary machinery transduces energy between chemical free energy and …

Molecular mechanism of ATP hydrolysis in an ABC transporter

M Prieß, H Göddeke, G Groenhof… - ACS central …, 2018 - ACS Publications
Hydrolysis of nucleoside triphosphate (NTP) plays a key role for the function of many
biomolecular systems. However, the chemistry of the catalytic reaction in terms of an atomic …