Induction of tumor cell autosis by myxoma virus-infected CAR-T and TCR-T cells to overcome primary and acquired resistance
Cytotoxicity of tumor-specific T cells requires tumor cell-to-T cell contact-dependent
induction of classic tumor cell apoptosis and pyroptosis. However, this may not trigger …
induction of classic tumor cell apoptosis and pyroptosis. However, this may not trigger …
Tumor-localized secretion of soluble PD1 enhances oncolytic virotherapy
MY Bartee, KM Dunlap, E Bartee - Cancer research, 2017 - AACR
Oncolytic virotherapy represents an attractive option for the treatment of a variety of
aggressive or refractory tumors. While this therapy is effective at rapidly debulking directly …
aggressive or refractory tumors. While this therapy is effective at rapidly debulking directly …
Non-labeled selective virus detection with novel SERS-active porous silver nanofilms fabricated by Electron Beam Physical Vapor Deposition
NN Durmanov, RR Guliev, AV Eremenko… - Sensors and Actuators B …, 2018 - Elsevier
Virus detection is often performed using antibody-based and polymerase chain reaction-
based techniques. Such methods have major deficiencies, caused by time-consuming and …
based techniques. Such methods have major deficiencies, caused by time-consuming and …
Use of precision-cut lung slices as an ex vivo tool for evaluating viruses and viral vectors for gene and oncolytic therapy
MCR Gerpe, JP van Vloten, LA Santry, J de Jong… - … therapy Methods & …, 2018 - cell.com
Organotypic slice cultures recapitulate many features of an intact organ, including cellular
architecture, microenvironment, and polarity, making them an ideal tool for the ex vivo study …
architecture, microenvironment, and polarity, making them an ideal tool for the ex vivo study …
Genetic Characterization of a Recombinant Myxoma Virus in the Iberian Hare (Lepus granatensis)
A Águeda-Pinto, A Lemos de Matos, M Abrantes… - Viruses, 2019 - mdpi.com
Myxomatosis is a lethal disease in wild European and domestic rabbits (Oryctolagus
cuniculus), which is caused by a Myxoma virus (MYXV) infection—a leporipoxvirus that is …
cuniculus), which is caused by a Myxoma virus (MYXV) infection—a leporipoxvirus that is …
Identification of host DEAD-box RNA helicases that regulate cellular tropism of oncolytic Myxoma virus in human cancer cells
Myxoma virus (MYXV), a Leporipoxvirus, is being developed as an oncolytic virotherapeutic
for the treatment of a variety of human cancers. MYXV tropism for human cancer cells is …
for the treatment of a variety of human cancers. MYXV tropism for human cancer cells is …
M062 is a host range factor essential for myxoma virus pathogenesis and functions as an antagonist of host SAMD9 in human cells
ABSTRACT Myxoma virus (MYXV) M062R is a functional homolog of the C7L family of host
range genes from orthopoxviruses. We constructed a targeted M062R-knockout-MYXV …
range genes from orthopoxviruses. We constructed a targeted M062R-knockout-MYXV …
M011L-deficient oncolytic myxoma virus induces apoptosis in brain tumor-initiating cells and enhances survival in a novel immunocompetent mouse model of …
Background Myxoma virus (MYXV) is a promising oncolytic agent and is highly effective
against immortalized glioma cells but less effective against brain tumor initiating cells …
against immortalized glioma cells but less effective against brain tumor initiating cells …
Myxoma virus sensitizes cancer cells to gemcitabine and is an effective oncolytic virotherapeutic in models of disseminated pancreatic cancer
Myxoma virus (MYXV) is a novel oncolytic virus that has been shown to replicate in
pancreatic cancer cells, but its efficacy in animal models of pancreatic cancer has not been …
pancreatic cancer cells, but its efficacy in animal models of pancreatic cancer has not been …
[HTML][HTML] Selective purging of human multiple myeloma cells from autologous stem cell transplantation grafts using oncolytic myxoma virus
Autologous stem cell transplantation and novel therapies have improved overall survival of
patients with multiple myeloma; however, most patients relapse and eventually succumb to …
patients with multiple myeloma; however, most patients relapse and eventually succumb to …