Induction of tumor cell autosis by myxoma virus-infected CAR-T and TCR-T cells to overcome primary and acquired resistance
Cytotoxicity of tumor-specific T cells requires tumor cell-to-T cell contact-dependent
induction of classic tumor cell apoptosis and pyroptosis. However, this may not trigger …
induction of classic tumor cell apoptosis and pyroptosis. However, this may not trigger …
Tumor-localized secretion of soluble PD1 enhances oncolytic virotherapy
MY Bartee, KM Dunlap, E Bartee - Cancer research, 2017 - AACR
Oncolytic virotherapy represents an attractive option for the treatment of a variety of
aggressive or refractory tumors. While this therapy is effective at rapidly debulking directly …
aggressive or refractory tumors. While this therapy is effective at rapidly debulking directly …
Non-labeled selective virus detection with novel SERS-active porous silver nanofilms fabricated by Electron Beam Physical Vapor Deposition
NN Durmanov, RR Guliev, AV Eremenko… - Sensors and Actuators B …, 2018 - Elsevier
Virus detection is often performed using antibody-based and polymerase chain reaction-
based techniques. Such methods have major deficiencies, caused by time-consuming and …
based techniques. Such methods have major deficiencies, caused by time-consuming and …
Use of precision-cut lung slices as an ex vivo tool for evaluating viruses and viral vectors for gene and oncolytic therapy
MCR Gerpe, JP van Vloten, LA Santry, J de Jong… - … therapy Methods & …, 2018 - cell.com
Organotypic slice cultures recapitulate many features of an intact organ, including cellular
architecture, microenvironment, and polarity, making them an ideal tool for the ex vivo study …
architecture, microenvironment, and polarity, making them an ideal tool for the ex vivo study …
Genetic Characterization of a Recombinant Myxoma Virus in the Iberian Hare (Lepus granatensis)
Myxomatosis is a lethal disease in wild European and domestic rabbits (Oryctolagus
cuniculus), which is caused by a Myxoma virus (MYXV) infection—a leporipoxvirus that is …
cuniculus), which is caused by a Myxoma virus (MYXV) infection—a leporipoxvirus that is …
Identification of host DEAD-box RNA helicases that regulate cellular tropism of oncolytic Myxoma virus in human cancer cells
Myxoma virus (MYXV), a Leporipoxvirus, is being developed as an oncolytic virotherapeutic
for the treatment of a variety of human cancers. MYXV tropism for human cancer cells is …
for the treatment of a variety of human cancers. MYXV tropism for human cancer cells is …
M011L-deficient oncolytic myxoma virus induces apoptosis in brain tumor-initiating cells and enhances survival in a novel immunocompetent mouse model of …
Background Myxoma virus (MYXV) is a promising oncolytic agent and is highly effective
against immortalized glioma cells but less effective against brain tumor initiating cells …
against immortalized glioma cells but less effective against brain tumor initiating cells …
M062 is a host range factor essential for myxoma virus pathogenesis and functions as an antagonist of host SAMD9 in human cells
ABSTRACT Myxoma virus (MYXV) M062R is a functional homolog of the C7L family of host
range genes from orthopoxviruses. We constructed a targeted M062R-knockout-MYXV …
range genes from orthopoxviruses. We constructed a targeted M062R-knockout-MYXV …
Myxoma virus sensitizes cancer cells to gemcitabine and is an effective oncolytic virotherapeutic in models of disseminated pancreatic cancer
Myxoma virus (MYXV) is a novel oncolytic virus that has been shown to replicate in
pancreatic cancer cells, but its efficacy in animal models of pancreatic cancer has not been …
pancreatic cancer cells, but its efficacy in animal models of pancreatic cancer has not been …
Oncolytic viral therapy as promising immunotherapy against glioma
D Hu, Y Tian, J Xu, D **e, Y Wang, M Liu… - MedComm–Future …, 2023 - Wiley Online Library
Glioma is a common primary central nervous system malignant tumor in clinical, traditional
methods such as surgery and chemoradiotherapy are not effective in treatment. Therefore …
methods such as surgery and chemoradiotherapy are not effective in treatment. Therefore …