Successful treatment of intrabronchial infection depends upon adequate transport of
antibiotics across the blood-bronchus barrier. This paper discusses the various influences …

Early studies of the penetration of antimicrobial agents into the sites of infection within the
respiratory tract have been criticized for methodological considerations, and the clinical …

Dental plaque samples from 40 children were screened for the presence of bacteria
resistant to amoxicillin. Fifteen children had used amoxicillin and 25 had not used any …

The rationale for measuring the concentrations of antimi-crobial agents at potential sites of
infection other than serum is that pathogens may be confined to sites which are sepa-rated …

Prolonged exposure to antibiotics at low concentration can promote processes associated
with bacterial biofilm formation, virulence and antibiotic resistance. This can be of high …

Effective antibiotic treatment for lung infections requires an amount of drug at the site of
infection sufficient to achieve or exceed the minimum inhibitory concentration (MIC) for that …

Synopsis: Amoxycillin 2 is an acid stable semisynthetic penicillin closely related to
ampicillin. Unlike pivampicillin and hetacillin, amoxycillin is not converted to ampicillin in the …

We conducted a systematic search to describe the current state of knowledge regarding the
utility of saliva for clinical pharmacokinetic monitoring (CPM) of antibiotics. Although the …

Purpose The current recommendations for the treatment of bacterial salivary gland infections
are mainly empirical. Therefore, an evidence-based literature review was conducted to …

The concentrations of two antibiotics, amoxycillin and ciprofloxacin, were measured by
microbiological assay in serum and in bronchial mucosa obtained at fibreoptic …