Systemic lupus erythematosus (SLE) is a disease characterized by dysregulation and
hyperreactivity of the immune response at various levels, including hyperactivation of …

Interleukin-6 (IL-6) plays a crucial role in systemic autoimmunity and pathologic
inflammation. Numerous studies have explored serum IL-6 levels in systemic lupus …

The majority of autoimmune diseases affect more women than men, suggesting an important
role for sex hormones in regulating immune response. Current research supports this idea …

Objective: Th1 and Th2 cells and their associated cytokines function in the pathogenesis of
systemic lupus erythematosus (SLE), but their exact roles are uncertain. We performed a …

Background Systemic lupus erythematosus (SLE) is an autoimmune disorder affecting
various organ systems with unknown etiology. Interleukin-6 (IL-6) and interferon-alpha (IFN …

Juvenile-onset lupus nephritis (LN) affects up to 80% of juvenile-onset systemic lupus
erythematosus patients (JSLE). As the exact role of human renal glomerular endothelial …

Childhood-onset systemic lupus erythematosus (cSLE) is a multisystem inflammatory
disease that can lead to severe clinical conditions resulting in early comorbidities. Several …

Background Systemic lupus erythematosus (SLE) is an inflammatory rheumatic disease
characterized by production of autoantibodies and organ damage. Elevated levels of …

Previous studies on the relationship between the circulating level of interleukin‐17 (IL‐17)
and disease activity in systemic lupus erythematosus (SLE) were contradictory. This study is …

Background Previous studies concerning the circulating interleukin-17 (IL-17) in systemic
lupus erythematosus (SLE) were contradictory. Aims To further precisely investigate …