The practice of polypharmacology is not a new concept but the approaches which are being
adopted for administering the two or more drugs together are varied from time to time …

Introduction: The hybridization of biologically active molecules is a powerful tool for drug
discovery used to target a variety of diseases. It offers the prospect of better drugs for the …

The widespread scrutiny of orthodox synthetic techniques for the fabrication of nitrogen-
embracing heteroatom segments has shifted scholar's focus to innovative environmentally …

We report a general method for the synthesis of chiral thiosquaramides, a class of
bifunctional catalysts not previously described in the literature. Thiosquaramides are found …

Two new coordination polymers, namely [Me3Sn (INA)](CP1) and [Me3Sn (NA)](CP2),
where INA= isonicotinic acid and NA= nicotinic acid, were characterized using infrared, UV …

An innovative, active Cu (II), Co (II), and Ni (II) complexes of Azomethine ligand [5-
(diethylamino)-2-hydroxyphenyl] methylidene} benzo hydrazide] were synthesized. The …

A general and greatly improved route is reported for the synthesis of a variety of
thiosquaramides from a common dithionated intermediate. Both diaryl thiosquaramides and …

Bifunctional secondary amine-thiourea organocatalysts were successfully applied in the
stereocontrolled synthesis of barbiturate-fused tetrahydropyrano scaffolds. Compared with …

Herein, we review developments in synthesis, structure, and biological (anti-cancer)
activities of 1, 1-bis (diphenylphosphino) methane (dppm) bridged homo-and …

Hepatocellular carcinoma (HCC) is a common cause of cancer death worldwide. Sorafenib,
a multikinase inhibitor, is the first-line drug approved by the Food and Drug Administration …