Mesenchymal stem cells

DC Ding, WC Shyu, SZ Lin - Cell transplantation, 2011 - journals.sagepub.com
Stem cells have two features: the ability to differentiate along different lineages and the
ability of self-renewal. Two major types of stem cells have been described, namely …

Adult mesenchymal stem cells and cell-based tissue engineering

RS Tuan, G Boland, R Tuli - Arthritis Res Ther, 2002 - Springer
The identification of multipotential mesenchymal stem cells (MSCs) derived from adult
human tissues, including bone marrow stroma and a number of connective tissues, has …

Comparison of human stem cells derived from various mesenchymal tissues: superiority of synovium as a cell source

Y Sakaguchi, I Sekiya, K Yagishita… - Arthritis & Rheumatism …, 2005 - Wiley Online Library
Objective To compare the properties of human mesenchymal stem cells (MSCs) isolated
from bone marrow, synovium, periosteum, skeletal muscle, and adipose tissue. Methods …

Characterization of the optimal culture conditions for clinical scale production of human mesenchymal stem cells

PA Sotiropoulou, SA Perez, M Salagianni… - Stem …, 2006 - academic.oup.com
Mesenchymal stem cells (MSCs) are multipotent cells defined by multilineage potential,
ease to gene modification, and immunosuppressive ability, thus holding promise for tissue …

Mesenchymal stem cells: isolation and therapeutics

A Alhadlaq, JJ Mao - Stem cells and development, 2004 - liebertpub.com
Mesenchymal stem cells (MSCs) are progenitors of all connective tissue cells. In adults of
multiple vertebrate species, MSCs have been isolated from bone marrow (BM) and other …

Hypoxia inhibits senescence and maintains mesenchymal stem cell properties through down-regulation of E2A-p21 by HIF-TWIST

CC Tsai, YJ Chen, TL Yew, LL Chen… - Blood, The Journal …, 2011 - ashpublications.org
Although low-density culture provides an efficient method for rapid expansion of human
mesenchymal stem cells (MSCs), MSCs enriched by this method undergo senescence and …

Mesenchymal stem cells: isolation, in vitro expansion and characterization

N Beyer Nardi, L da Silva Meirelles - Stem cells, 2006 - Springer
Mesenchymal stem cells (MSC), one type of adult stem cell, are easy to isolate, culture, and
manipulate in ex vivo culture. These cells have great plasticity and the potential for …

Immortality of cell lines: challenges and advantages of establishment

M Irfan Maqsood, MM Matin, AR Bahrami… - Cell biology …, 2013 - Wiley Online Library
Cellular immortality happens upon impairment of cell‐cycle checkpoint pathways
(p53/p16/pRb), reactivation or up‐regulation of telomerase enzyme, or upregulation of some …

Marrow-isolated adult multilineage inducible (MIAMI) cells, a unique population of postnatal young and old human cells with extensive expansion and differentiation …

G D'Ippolito, S Diabira, GA Howard… - Journal of cell …, 2004 - journals.biologists.com
We report here the isolation of a population of non-transformed pluripotent human cells from
bone marrow after a unique expansion/selection procedure. This procedure was designed …

Mesenchymal stem/stromal cells derived from human and animal perinatal tissues—origins, characteristics, signaling pathways, and clinical trials

M Kulus, R Sibiak, K Stefańska, M Zdun… - Cells, 2021 - mdpi.com
Mesenchymal stem/stromal cells (MSCs) are currently one of the most extensively
researched fields due to their promising opportunity for use in regenerative medicine. There …