STS-NLSP: a network-based label space partition method for predicting the specificity of membrane transporter substrates using a hybrid feature of structural and …
X Wang, X Zhu, M Ye, Y Wang, CD Li… - … in bioengineering and …, 2019 - frontiersin.org
Membrane transport proteins play crucial roles in the pharmacokinetics of substrate drugs,
the drug resistance in cancer and are vital to the process of drug discovery, development …
the drug resistance in cancer and are vital to the process of drug discovery, development …
A deep learning based two-layer predictor to identify enhancers and their strength
D Zhu, W Yang, D Xu, H Li, Y Zhao, D Li - Methods, 2023 - Elsevier
The enhancer is a DNA sequence that can increase the activity of promoters and thus speed
up the frequency of gene transcription. The enhancer plays an essential role in activating …
up the frequency of gene transcription. The enhancer plays an essential role in activating …
Development and validation of a computational model ensemble for the early detection of BCRP/ABCG2 substrates during the drug design stage
Breast Cancer Resistance Protein (BCRP) is an ATP-dependent efflux transporter linked to
the multidrug resistance phenomenon in many diseases such as epilepsy and cancer and a …
the multidrug resistance phenomenon in many diseases such as epilepsy and cancer and a …