Local anesthetic systemic toxicity (LAST) is a life-threatening adverse event that may occur
after the administration of local anesthetic drugs through a variety of routes. Increasing use …

Abstract The American Society of Regional Anesthesia and Pain Medicine's Third Practice
Advisory on local anesthetic systemic toxicity is an interim update from its 2010 advisory …

Despite advances in clinical practice, local anaesthetic systemic toxicity continues to occur
with the therapeutic use of local anaesthesia. Patterns of presentation have evolved over …

This review summarizes presenting features, management, and outcomes of local
anesthetic systemic toxicity (LAST) from published cases and those submitted to online …

Background: The objective of this narrative review of local anesthetic systemic toxicity is to
provide an update on its prevention, diagnosis, and management. Methods: The authors …

Local anesthetics are essential medications for the conduction of dermatological
procedures. They stop the depolarization of nerve fibers and are divided into two main …

Introduction Emergency clinicians utilize local anesthetics for a variety of procedures in the
emergency department (ED) setting. Local anesthetic systemic toxicity (LAST) is a potentially …

Regional anesthesia is an integral component of successful orthopedic surgery. Neuraxial
anesthesia is commonly used for surgical anesthesia while peripheral nerve blocks are …

As an increasing number of orthopedic surgeries move from inpatient to outpatient settings,
changes within anesthetic practices need to follow. 1 In ambulatory surgery, decreasing …

This article provides a concise overview of local anesthetic systemic toxicity, its history,
mechanisms, risk factors, prevention, clinical presentation, and treatment, with a special …