The biomedical uses of inositols: A nutraceutical approach to metabolic dysfunction in aging and neurodegenerative diseases

AJ López-Gambero, C Sanjuan, PJ Serrano-Castro… - Biomedicines, 2020 - mdpi.com
Inositols are sugar-like compounds that are widely distributed in nature and are a part of
membrane molecules, participating as second messengers in several cell-signaling …

The role of glycosyl–phosphatidylinositol in signal transduction

DR Jones, I Varela-Nieto - The International Journal of Biochemistry & Cell …, 1998 - Elsevier
Glycosyl–phosphatidylinositol (GPI) lipids have a structural role as protein anchors to the
cell surface. In addition, they are implicated in hormone, growth factor and cytokine signal …

Differential gene expression in astrocytes from human normal and glaucomatous optic nerve head analyzed by cDNA microarray

MR Hernandez, OA Agapova, P Yang… - Glia, 2002 - Wiley Online Library
Recent advances in cDNA microarray technology have made it possible to analyze
expression of several thousand genes at the same time. Using this technique, gene …

Do β‐Defensins and Other Antimicrobial Peptides Play a Role in Neuroimmune Function and Neurodegeneration?

WM Williams, RJ Castellani, A Weinberg… - The Scientific World …, 2012 - Wiley Online Library
It is widely accepted that the brain responds to mechanical trauma and development of most
neurodegenerative diseases with an inflammatory sequelae that was once thought …

25-Hydroxycholesterol has a dual effect on the proliferation of cultured rat astrocytes

E Velázquez, A Santos, A Montes, E Blázquez… - …, 2006 - Elsevier
We examined the effects of 25-OH-cholesterol on the growth of cultured rat astrocytes in the
presence of lipoprotein-deficient serum (LPDS). 25-OH-cholesterol at 0.5–8μM induced an …

Signalling events mediating the activation of protein kinase C by interleukin-2 in cytotoxic T cells

Y Lu, P Morley, JP Durkin - Cellular signalling, 1999 - Elsevier
Interleukin-2 (IL-2) plays a vital role in the generation and regulation of the immune
response, including important aspects of T cell survival. IL-2-mediated survival of T cells …

Insulin-mimicking bioactivities of acylated inositol glycans in several mouse models of diabetes with or without obesity

S Suzuki, C Suzuki, Y Hinokio, Y Ishigaki, H Katagiri… - PLoS …, 2014 - journals.plos.org
Insulin-mimetic species of low molecular weight are speculated to mediate some
intracellular insulin actions. These inositol glycans, which are generated upon insulin …

Glucose and several mitogenic agents modulate the glucagon-like peptide-2 receptor expression in cultured rat astrocytes

E Velázquez, Y Le Baut Ayuso… - Journal of …, 2022 - content.iospress.com
Background: Glucagon-like peptide-2 (GLP-2) is an intestinal trophic factor that induces
astrocyte proliferation through its own receptor (GLP-2R), but the control of its expression is …

Glucagon-like peptide-2 (GLP-2) modulates the cGMP Signalling pathway by regulating the expression of the soluble guanylyl cyclase receptor subunits in cultured rat …

E Velázquez, E Blázquez, JM Ruiz-Albusac - Molecular neurobiology, 2012 - Springer
The aim of this work was to study the effect of glucagon-like peptide-2 (GLP-2) on the cyclic
guanosine monophosphate (cGMP) signalling pathway and whether insulin or epidermal …

[PDF][PDF] Insulin-Mimicking Bioactivities of Acylated Inositol Glycans in Several Mouse Models of

S Suzuki, C Suzuki, Y Hinokio, Y Ishigaki, H Katagiri - 2014 - academia.edu
Insulin-mimetic species of low molecular weight are speculated to mediate some
intracellular insulin actions. These inositol glycans, which are generated upon insulin …