Translational opportunities and challenges of invasive electrodes for neural interfaces
Invasive brain–machine interfaces can restore motor, sensory and cognitive functions.
However, their clinical adoption has been hindered by the surgical risk of implantation and …
However, their clinical adoption has been hindered by the surgical risk of implantation and …
Achieving long-term stability of thin-film electrodes for neurostimulation
P Oldroyd, GG Malliaras - Acta Biomaterialia, 2022 - Elsevier
Implantable electrodes that can reliably measure brain activity and deliver an electrical
stimulus to a target tissue are increasingly employed to treat various neurological diseases …
stimulus to a target tissue are increasingly employed to treat various neurological diseases …
High-density μLED-based optical cochlear implant with improved thermomechanical behavior
This study reports the realization of an optical cochlear implant (oCI) with optimized
thermomechanical properties for optogenetic experiments. The oCI probe comprises 144 …
thermomechanical properties for optogenetic experiments. The oCI probe comprises 144 …
Ultra-capacitive carbon neural probe allows simultaneous long-term electrical stimulations and high-resolution neurotransmitter detection
We present a new class of carbon-based neural probes that consist of homogeneous glassy
carbon (GC) microelectrodes, interconnects and bump pads. These electrodes have purely …
carbon (GC) microelectrodes, interconnects and bump pads. These electrodes have purely …
Chronic neural probe for simultaneous recording of single-unit, multi-unit, and local field potential activity from multiple brain sites
Objective. Drug resistant focal epilepsy can be treated by resecting the epileptic focus
requiring a precise focus localisation using stereoelectroencephalography (SEEG) probes …
requiring a precise focus localisation using stereoelectroencephalography (SEEG) probes …
Insulation lifetime improvement of polyimide thin film neural implants
Objective. This work deals with studying and improving the insulation lifetime of polyimide-
insulated thin film neural implants, or related polyimide-based medical implants. Approach …
insulated thin film neural implants, or related polyimide-based medical implants. Approach …
Incorporation of Silicon Carbide and Diamond‐Like Carbon as Adhesion Promoters Improves In Vitro and In Vivo Stability of Thin‐Film Glassy Carbon …
M Vomero, E Castagnola, JS Ordonez… - Advanced …, 2018 - Wiley Online Library
Thin‐film neural devices are an appealing alternative to traditional implants, although their
chronic stability remains matter of investigation. In this study, a chronically stable class of …
chronic stability remains matter of investigation. In this study, a chronically stable class of …
Improved polyimide thin-film electrodes for neural implants
JS Ordonez, C Boehler, M Schuettler… - … Conference of the …, 2012 - ieeexplore.ieee.org
Thin-film electrode arrays for neural implants are necessary when large integration densities
of stimulating or recording channels are required. However, delamination of the metallic …
of stimulating or recording channels are required. However, delamination of the metallic …
Silicone rubber and thin-film polyimide for hybrid neural interfaces—A MEMS-based adhesion promotion technique
JS Ordonez, C Boehler, M Schuettler… - 2013 6th International …, 2013 - ieeexplore.ieee.org
Strong permanent adhesion between thin-film polyimide (BPDA-PPD) and silicone rubber
(MED-1000) was achieved through deposition of a chemically-transitive intermediate …
(MED-1000) was achieved through deposition of a chemically-transitive intermediate …
Evaluation of adhesion promoters for Parylene C on gold metallization
V Radun, RP Von Metzen, T Stieglitz… - Current Directions in …, 2015 - degruyter.com
Delamination of thin film polymeric coatings from metallization layers is a common cause of
failure in biomedical implants. To address the problem, different adhesion promotion …
failure in biomedical implants. To address the problem, different adhesion promotion …