Phloretin, as a potent anticancer compound: from chemistry to cellular interactions

HS Tuli, P Rath, A Chauhan, S Ramniwas, K Vashishth… - Molecules, 2022 - mdpi.com
Phloretin is a natural dihydrochalcone found in many fruits and vegetables, especially in
apple tree leaves and the Manchurian apricots, exhibiting several therapeutic properties …

Dihydrochalcones: Methods of acquisition and pharmacological properties—A first systematic review

M Stompor, D Broda, A Bajek-Bil - Molecules, 2019 - mdpi.com
Dihydrochalcones are a class of secondary metabolites, for which demand in biological and
pharmacological applications is still growing. They posses several health-endorsing …

Hibiscus, rooibos, and yerba mate for healthy aging: A review on the attenuation of in vitro and in vivo markers related to oxidative stress, glycoxidation, and …

MT Nogueira Silva Lima, E Boulanger, FJ Tessier… - Foods, 2022 - mdpi.com
The world is currently undergoing a demographic change towards an increasing number of
elderly citizens. Aging is characterized by a temporal decline in physiological capacity, and …

[HTML][HTML] Rooibos, a supportive role to play during the COVID-19 pandemic?

NS Abdul, JL Marnewick - Journal of functional foods, 2021 - Elsevier
This article presents the potential health benefits of Rooibos to be considered a support
during the COVID-19 pandemic. The recent pandemic of COVID-19 has led to severe …

Modular metabolic engineering for production of phloretic acid, phloretin and phlorizin in Escherichia coli

X Liu, J Liu, D Lei, GR Zhao - Chemical Engineering Science, 2022 - Elsevier
Phloretic acid, phloretin and phlorizin (phloretin 2′-O-glucoside), plant-derived natural
products, are well known for human health benefits and medical application. Here, we …

The effects of flavonoids in experimental sepsis: A systematic review and meta‐analysis

E de Oliveira Rodrigues Junior… - Phytotherapy …, 2023 - Wiley Online Library
Sepsis is a host's dysregulated immune response to an infection associated with systemic
inflammation and excessive oxidative stress, which can cause multiple organ failure and …

[HTML][HTML] Trends in Rooibos Tea (Aspalathus linearis) research (1994–2018): A scientometric assessment

IL Elisha, A Viljoen - South African Journal of Botany, 2021 - Elsevier
This bibliometric assessment aimed to gain insight into the publication landscape over a 25-
year period on one of South Africa's most coveted indigenous plants, Aspalathus linearis …

Promising medicinal plants with diuretic potential used in Brazil: State of the art, challenges, and prospects

P de Souza, LNB Mariano… - Planta …, 2021 - thieme-connect.com
Medicinal plants are used in traditional medicine to treat a wide range of ailments. The
knowledge of them is handed down from generation to generation and is described in …

Nitric oxide and Ca2+-activated high-conductance K+ channels mediate nothofagin-induced endothelium-dependent vasodilation in the perfused rat kidney

AAM Marques, CHF da Silva, P de Souza… - Chemico-Biological …, 2020 - Elsevier
Nothofagin is a natural 3′-C-β-D-glucoside of the polyphenol phloretin that is mainly found
in Aspalathus linearis, Nothofagus fusca, and Leandra dasytricha. In recent years …

Aspalathin: a rare dietary dihydrochalcone from Aspalathus linearis (rooibos tea)

SK Chaudhary, M Sandasi, F Makolo… - Phytochemistry …, 2021 - Springer
Abstract Aspalathin (2′, 3, 4, 4′, 6′-pentahydroxy-3′-C-β-D-
glucopyranosyldihydrochalcone) is a natural C-linked glucosyl dihydrochalcone present in …