A characteristic of many neurodegenerative diseases, including Alzheimer's disease (AD),
Parkinson's disease (PD), Huntington's disease (HD), and amyotrophic lateral sclerosis …

Nitric oxide (NO), an enzymatic product of nitric oxide synthase (NOS), has been associated
with a variety of neurological diseases such as Alzheimer's disease (AD). NO has long been …

The primate frontal lobe (FL) is sensitive to aging-related neurocognitive decline. However,
the aging-associated molecular mechanisms remain unclear. Here, using physiologically …

Alzheimer's disease (AD) is one of the most prevalent neurodegenerative diseases, yet
current therapeutic treatments are inadequate due to a complex disease pathogenesis. The …

Alzheimer's disease (AD) is a complex neurodegenerative disorder characterized by
extracellular plaques containing amyloid β (Aβ)-protein and intracellular tangles containing …

Here we elucidate the effect of Alzheimer disease (AD)-predisposing genetic backgrounds,
APOE4, PSEN1ΔE9, and APPswe, on functionality of human microglia-like cells (iMGLs) …

Alzheimer's disease (AD) is a neurodegenerative disorder involving the loss of neurons in
the brain which leads to progressive memory loss and behavioral changes. To date, there …

Abstract About 1.2 to 33% of high-altitude populations suffer from Monge's disease or
chronic mountain sickness (CMS). Number of factors such as age, sex, and population of …

An early substantial loss of basal forebrain cholinergic neurons (BFCNs) is a constant
feature of Alzheimer's disease (AD) and is associated with deficits in spatial learning and …

Neurotrophins (NTs) are members of a neuronal growth factor protein family whose action is
mediated by the tropomyosin receptor kinase (TRK) receptor family receptors and the p75 …