[HTML][HTML] Mitochondrial metal ion transport in cell metabolism and disease

X Wang, P An, Z Gu, Y Luo, J Luo - International Journal of Molecular …, 2021 - mdpi.com
Mitochondria are vital to life and provide biological energy for other organelles and cell
physiological processes. On the mitochondrial double layer membrane, there are a variety of …

[HTML][HTML] Chemotherapy resistance: role of mitochondrial and autophagic components

E Bahar, SY Han, JY Kim, H Yoon - Cancers, 2022 - mdpi.com
Simple Summary Chemotherapy resistance is a common occurrence during cancer
treatment that cancer researchers are attempting to understand and overcome. Mitochondria …

[HTML][HTML] Mechanistic correlation between mitochondrial permeability transition pores and mitochondrial ATP dependent potassium channels in ischemia reperfusion

R Behera, V Sharma, AK Grewal, A Kumar… - Biomedicine & …, 2023 - Elsevier
Mitochondrial dysfunction is one of the fundamental causes of ischemia reperfusion (I/R)
damage. I/R refers to the paradoxical progression of cellular dysfunction and death that …

Mitochondrial ion channels

I Szabo, A Szewczyk - Annual Review of Biophysics, 2023 - annualreviews.org
Mitochondria are involved in multiple cellular tasks, such as ATP synthesis, metabolism,
metabolite and ion transport, regulation of apoptosis, inflammation, signaling, and …

[HTML][HTML] Mitochondrial potassium channels as druggable targets

A Wrzosek, B Augustynek, M Żochowska, A Szewczyk - Biomolecules, 2020 - mdpi.com
Mitochondrial potassium channels have been described as important factors in cell pro-life
and death phenomena. The activation of mitochondrial potassium channels, such as ATP …

TMBIM5 loss of function alters mitochondrial matrix ion homeostasis and causes a skeletal myopathy

L Zhang, F Dietsche, B Seitaj… - Life science …, 2022 - life-science-alliance.org
Ion fluxes across the inner mitochondrial membrane control mitochondrial volume, energy
production, and apoptosis. TMBIM5, a highly conserved protein with homology to putative …

A mini-review on ion fluxes that regulate NLRP3 inflammasome activation

C Li, M Chen, X He, D Ouyang - Acta biochimica et biophysica …, 2021 - academic.oup.com
The activation of NLR family pyrin domain containing 3 (NLRP3) inflammasome can be
induced by a wide spectrum of activators. This is unlikely achieved by the binding of different …

COVID-19. Pandemic surgery guidance

BLDM Brücher, G Nigri, A Tinelli, J Florencio… - 4 OPEN, 2020 - iris.uniroma1.it
Based on high quality surgery and scientific data, scientists and surgeons are committed to
protecting patients as well as healthcare staff and hereby provide this Guidance to address …

Post-translational modifications and protein quality control of mitochondrial channels and transporters

A Kadam, P Jadiya, D Tomar - Frontiers in Cell and Developmental …, 2023 - frontiersin.org
Mitochondria play a critical role in energy metabolism and signal transduction, which is
tightly regulated by proteins, metabolites, and ion fluxes. Metabolites and ion homeostasis …

Current challenges of mitochondrial potassium channel research

B Kulawiak, A Szewczyk - Frontiers in Physiology, 2022 - frontiersin.org
In this paper, the current challenges of mitochondrial potassium channels research were
critically reviewed. Even though recent progress in understanding K+ traffic in mitochondria …