The pulmonary circulation responds to hypoxia with vasoconstriction, a mechanism that
helps to adapt to short-lived hypoxic episodes. When sustained, hypoxic pulmonary …

Ethnopharmacological relevance Inflammation is a complex mechanism employed by the
body to promote healing and restoration to normal function in the event of injury. Eleven …

Acute hypoxia and chronic hypoxia induce pulmonary vasoconstriction. While hypoxic
pulmonary vasoconstriction is a physiological response if parts of the lung are affected …

Data-driven analyses are increasingly valued in modern medicine. We integrate quantitative
proteomics and transcriptomics from over 1,000 post-mortem brains from six cohorts …

The endogenous methylated derivative of ʟ-arginine, N ω, N ω′-dimethyl-ʟ-arginine
(asymmetric dimethylarginine, ADMA), an independent risk factor in many diseases, inhibits …

Abstract Ethnopharmacological relevance Harpalyce brasiliana Benth (Leguminosae) is a
shrub endemic to Brazil, popularly known as “snake's root.” This species is used in folk …

Objective To investigate the anti-inflammatory activity of different fractions and glutinol
(isolated compound), using nitric oxide synthase and cyclooxygenase (COX) inhibition as an …

The contribution of nitric oxide synthases (NOSs) to the pathophysiology of several
neuropsychiatric disorders is recognized, but the role of their regulators, dimethylarginine …

Objective: Chronic hypoxia causes pulmonary vasoconstriction leading to pulmonary
hypertension and right ventricular hypertrophy. Asymmetric dimethylarginine (ADMA) is an …

Rheumatoid arthritis (RA) patients have increased risk of cardiovascular disease (CVD)
death. Elevated asymmetric dimethylarginine (ADMA) levels have been reported to be an …