Abstract Non-enzymatic chitinase-3 like-protein-1 (CHI3L1) belongs to glycoside hydrolase
family 18. It binds to chitin, heparin, and hyaluronic acid, and is regulated by extracellular …

Systemic corticosteroid use to manage uncontrolled asthma and its associated healthcare
burden may account for important health-related adverse effects. We conducted a systematic …

ABSTRACT COPD is a major global concern, increasingly so in the context of ageing
populations. The role of infections in disease pathogenesis and progression is known to be …

Although eosinophilic inflammation is characteristic of asthma pathogenesis, neutrophilic
inflammation is also marked, and eosinophils and neutrophils can coexist in some cases …

Asthma is a heterogenous disease characterized by multiple phenotypes driven by different
mechanisms. The implementation of precision medicine in the management of asthma …

The potential of precision medicine in allergy and asthma has only started to be explored. A
significant clarification in the pathophysiology of rhinitis, chronic rhinosinusitis, asthma, food …

Chitinase 3-like 1 (also known as CHI3L1 or YKL-40) is a mammalian chitinase that has no
enzymatic activity, but has the ability to bind to chitin, the polymer of N-acetylglucosamine …

Airway remodeling is accepted to be a determining component within the natural history of
asthma. It is a phenomenon characterized by changes in the airways structures that marches …

Background Serum chitotriosidase is a promising biomarker that has shown high specificity
and sensitivity in patients with sarcoidosis. The aim of this study was to investigate …

The role of chitinases has been focused as potential biomarkers in a wide number of
inflammatory diseases, in monitoring active disease state, and predicting prognosis and …