Gold nanoparticles in chemical and biological sensing

K Saha, SS Agasti, C Kim, X Li, VM Rotello - Chemical reviews, 2012‏ - ACS Publications
1. INTRODUCTION Detection of chemical and biological agents plays a fundamental role in
biomedical, forensic and environmental sciences 1− 4 as well as in anti bioterrorism …

Functionalizing nanoparticles with biological molecules: develo** chemistries that facilitate nanotechnology

KE Sapsford, WR Algar, L Berti, KB Gemmill… - Chemical …, 2013‏ - ACS Publications
(5aR, 11bS)-4, 5, 5a, 6, 7, 11b-Hexahydro-2-propyl-3-thia-5-azacyclopent-1-ena [c]
phenanthrene-9, 10-diol (A-86929): a potent and selective dopamine D1 agonist that …

Chemical basis of interactions between engineered nanoparticles and biological systems

Q Mu, G Jiang, L Chen, H Zhou, D Fourches… - Chemical …, 2014‏ - ACS Publications
As defined by the European Commission, a nanomaterial is a natural, an incidental, or a
manufactured material containing particles in an unbound state or as an aggregate or …

Protein− nanoparticle interactions: opportunities and challenges

M Mahmoudi, I Lynch, MR Ejtehadi… - Chemical …, 2011‏ - ACS Publications
In recent years, the fabrication of nanomaterials and exploration of their properties have
attracted the attention of all branches of science, such as physics, chemistry, biology, and …

Gold nanoparticles for nucleic acid delivery

Y Ding, Z Jiang, K Saha, CS Kim, ST Kim, RF Landis… - Molecular therapy, 2014‏ - cell.com
Gold nanoparticles provide an attractive and applicable scaffold for delivery of nucleic acids.
In this review, we focus on the use of covalent and noncovalent gold nanoparticle …

Interaction of gold nanoparticles with common human blood proteins

SHDP Lacerda, JJ Park, C Meuse, D Pristinski… - ACS …, 2010‏ - ACS Publications
In order to better understand the physical basis of the biological activity of nanoparticles
(NPs) in nanomedicine applications and under conditions of environmental exposure, we …

The role of surface functionality in determining nanoparticle cytotoxicity

ST Kim, K Saha, C Kim, VM Rotello - Accounts of chemical …, 2013‏ - ACS Publications
Surface properties dictate the behavior of nanomaterials in vitro, in vivo, and in the
environment. Such properties include surface charge and hydrophobicity. Also key are more …

Shape-dependent biomimetic inhibition of enzyme by nanoparticles and their antibacterial activity

SH Cha, J Hong, M McGuffie, B Yeom, JS VanEpps… - ACS …, 2015‏ - ACS Publications
Enzyme inhibitors are ubiquitous in all living systems, and their biological inhibitory activity
is strongly dependent on their molecular shape. Here, we show that small zinc oxide …

Detection and identification of proteins using nanoparticle–fluorescent polymer 'chemical nose'sensors

CC You, OR Miranda, B Gider, PS Ghosh, IB Kim… - Nature …, 2007‏ - nature.com
A sensor array containing six non-covalent gold nanoparticle–fluorescent polymer
conjugates has been created to detect, identify and quantify protein targets. The polymer …

Tuning payload delivery in tumour cylindroids using gold nanoparticles

B Kim, G Han, BJ Toley, C Kim, VM Rotello… - Nature …, 2010‏ - nature.com
Nanoparticles have great potential as controllable drug delivery vehicles because of their
size and modular functionality. Timing and location are important parameters when …