The microbiota-gut-brain axis

JF Cryan, KJ O'Riordan, CSM Cowan… - Physiological …, 2019 - journals.physiology.org
I. INTRODUCTION 1877 II. STUDYING THE... 1881 III. MICROBIOTA-GUT-BRAIN AXIS...
1907 IV. PATHWAYS OF COMMUNICATION 1911 V. MICROBIOTA AND SYNAPTIC... 1929 …

[HTML][HTML] Multi-omics of the gut microbial ecosystem in inflammatory bowel diseases

J Lloyd-Price, C Arze, AN Ananthakrishnan… - Nature, 2019 - nature.com
Inflammatory bowel diseases, which include Crohn's disease and ulcerative colitis, affect
several million individuals worldwide. Crohn's disease and ulcerative colitis are complex …

GTDB: an ongoing census of bacterial and archaeal diversity through a phylogenetically consistent, rank normalized and complete genome-based taxonomy

DH Parks, M Chuvochina, C Rinke… - Nucleic acids …, 2022 - academic.oup.com
Abstract The Genome Taxonomy Database (GTDB; https://gtdb. ecogenomic. org) provides a
phylogenetically consistent and rank normalized genome-based taxonomy for prokaryotic …

Extending and improving metagenomic taxonomic profiling with uncharacterized species using MetaPhlAn 4

A Blanco-Míguez, F Beghini, F Cumbo, LJ McIver… - Nature …, 2023 - nature.com
Metagenomic assembly enables new organism discovery from microbial communities, but it
can only capture few abundant organisms from most metagenomes. Here we present …

Microbiome definition re-visited: old concepts and new challenges

G Berg, D Rybakova, D Fischer, T Cernava… - Microbiome, 2020 - Springer
The field of microbiome research has evolved rapidly over the past few decades and has
become a topic of great scientific and public interest. As a result of this rapid growth in …

GTDB-Tk: a toolkit to classify genomes with the Genome Taxonomy Database

PA Chaumeil, AJ Mussig, P Hugenholtz, DH Parks - 2020 - academic.oup.com
Abstract Summary The Genome Taxonomy Database Toolkit (GTDB-Tk) provides objective
taxonomic assignments for bacterial and archaeal genomes based on the GTDB. GTDB-Tk …

CheckM2: a rapid, scalable and accurate tool for assessing microbial genome quality using machine learning

A Chklovski, DH Parks, BJ Woodcroft, GW Tyson - Nature Methods, 2023 - nature.com
Advances in sequencing technologies and bioinformatics tools have dramatically increased
the recovery rate of microbial genomes from metagenomic data. Assessing the quality of …

A unified catalog of 204,938 reference genomes from the human gut microbiome

A Almeida, S Nayfach, M Boland, F Strozzi… - Nature …, 2021 - nature.com
Comprehensive, high-quality reference genomes are required for functional characterization
and taxonomic assignment of the human gut microbiota. We present the Unified Human …

The person-to-person transmission landscape of the gut and oral microbiomes

M Valles-Colomer, A Blanco-Míguez, P Manghi… - Nature, 2023 - nature.com
The human microbiome is an integral component of the human body and a co-determinant
of several health conditions,. However, the extent to which interpersonal relations shape the …

MetaBAT 2: an adaptive binning algorithm for robust and efficient genome reconstruction from metagenome assemblies

DD Kang, F Li, E Kirton, A Thomas, R Egan, H An… - PeerJ, 2019 - peerj.com
We previously reported on MetaBAT, an automated metagenome binning software tool to
reconstruct single genomes from microbial communities for subsequent analyses of …