[HTML][HTML] Natural therapeutics and nutraceuticals for lung diseases: traditional significance, phytochemistry, and pharmacology
Background Lung diseases including chronic obstructive pulmonary disease (COPD),
infections like influenza, acute respiratory distress syndrome (ARDS), asthma and …
infections like influenza, acute respiratory distress syndrome (ARDS), asthma and …
Preparation and evaluation of chitosan/PVA based hydrogel films loaded with honey for wound healing application
In the present study, chitosan/polyvinyl alcohol (PVA)-based honey hydrogel films were
developed for potential wound healing application. The hydrogel films were developed by a …
developed for potential wound healing application. The hydrogel films were developed by a …
[HTML][HTML] Modern drug discovery applications for the identification of novel candidates for COVID-19 infections
In early December 2019, a large pneumonia epidemic occurred in Wuhan, China. The World
Health Organization is concerned about the outbreak of another coronavirus with the …
Health Organization is concerned about the outbreak of another coronavirus with the …
Identification of novel peptide inhibitors for the KRas-G12C variant to prevent oncogenic signaling
Kirsten rat sarcoma viral oncogene homolog (KRas) activating mutations are common in
solid tumors, accounting for 90%, 45%, and 35% of pancreatic, colorectal, and lung cancers …
solid tumors, accounting for 90%, 45%, and 35% of pancreatic, colorectal, and lung cancers …
[HTML][HTML] Virtual screening and molecular dynamics simulation analysis of Forsythoside A as a plant-derived inhibitor of SARS-CoV-2 3CLpro
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a more severe strain of
coronavirus (CoV) that was first emerged in China in 2019. Available antiviral drugs could …
coronavirus (CoV) that was first emerged in China in 2019. Available antiviral drugs could …
In vitro and in silico characterization of curcumin-loaded chitosan–PVA hydrogels: antimicrobial and potential wound healing activity
Curcumin has been used in traditional medicine forages. The present study aimed to
develop a curcumin-based hydrogel system and assess its antimicrobial potential and …
develop a curcumin-based hydrogel system and assess its antimicrobial potential and …
Study of MDM2 as Prognostic Biomarker in Brain-LGG Cancer and Bioactive Phytochemicals Inhibit the p53-MDM2 Pathway: A Computational Drug Development …
An evaluation of the expression and predictive significance of the MDM2 gene in brain lower-
grade glioma (LGG) cancer was carried out using onco-informatics pipelines. Several …
grade glioma (LGG) cancer was carried out using onco-informatics pipelines. Several …
Design and synthesis of new flavonols as dual ɑ-amylase and ɑ-glucosidase inhibitors: structure-activity relationship, drug-likeness, in vitro and in silico studies
In this study, a library of new intriguing flavonol derivatives (1–17) was designed and
synthesized through a facile route involving Algar-Flynn-Oyamada reaction in a one-pot …
synthesized through a facile route involving Algar-Flynn-Oyamada reaction in a one-pot …
Marine natural compounds as potential CBP bromodomain inhibitors for treating cancer: an in-silico approach using molecular docking, ADMET, molecular dynamics …
The cAMP-responsive element binding protein (CREB) binding protein (CBP), a
bromodomain-containing protein, engages with multiple transcription factors and enhances …
bromodomain-containing protein, engages with multiple transcription factors and enhances …
[HTML][HTML] Predicting Meridian in Chinese traditional medicine using machine learning approaches
Plant-derived nature products, known as herb formulas, have been commonly used in
Traditional Chinese Medicine (TCM) for disease prevention and treatment. The herbs have …
Traditional Chinese Medicine (TCM) for disease prevention and treatment. The herbs have …