Glycomimetics versus multivalent glycoconjugates for the design of high affinity lectin ligands

S Cecioni, A Imberty, S Vidal - Chemical reviews, 2015 - ACS Publications
One could certainly highlight a conceptual resemblance between social interactions as the
basis of societies and civilizations and the ability of molecules to interact in a noncovalent …

The copper (I)-catalyzed alkyne-azide cycloaddition (CuAAC)“click” reaction and its applications. An overview

L Liang, D Astruc - Coordination Chemistry Reviews, 2011 - Elsevier
A short overview of the copper (I)-catalyzed azide alkyne cycloaddition (CuAAC), the most
used “click” reaction, is presented, including the introduction of the “click” concept, the …

Multivalent glycoconjugates as anti-pathogenic agents

A Bernardi, J Jiménez-Barbero, A Casnati… - Chemical Society …, 2013 - pubs.rsc.org
Multivalency plays a major role in biological processes and particularly in the relationship
between pathogenic microorganisms and their host that involves protein–glycan recognition …

From carbohydrate leads to glycomimetic drugs

B Ernst, JL Magnani - Nature reviews Drug discovery, 2009 - nature.com
Carbohydrates are the most abundant natural products. Besides their role in metabolism
and as structural building blocks, they are fundamental constituents of every cell surface …

Carbohydrates in supramolecular chemistry

M Delbianco, P Bharate, S Varela-Aramburu… - Chemical …, 2016 - ACS Publications
Carbohydrates are involved in a variety of biological processes. The ability of sugars to form
a large number of hydrogen bonds has made them important components for …

Dendrimers derived from 1→ 3 branching motifs

GR Newkome, C Shreiner - Chemical reviews, 2010 - ACS Publications
In 2008, we overviewed1 poly (amido amine) s, polypropylenimines, and related dendrimers
and dendrons possessing diverse 1 f 2 branching patterns that were predominately made …

“Click” methodologies: efficient, simple and greener routes to design dendrimers

G Franc, AK Kakkar - Chemical Society Reviews, 2010 - pubs.rsc.org
Designing dendrimers that are monodisperse hyperbranched macromolecules and offer
significant potential in numerous scientific fields, is becoming a major topical area in modern …

Maximising multivalency effects in protein–carbohydrate interactions

RJ Pieters - Organic & biomolecular chemistry, 2009 - pubs.rsc.org
Multivalent carbohydrates are currently produced in many forms ranging from dendrimers,
polymers, micelles, vesicles, nanoparticles to functionalized nanotubes, in order to enhance …

Design and creativity in synthesis of multivalent neoglycoconjugates

YM Chabre, R Roy - Advances in carbohydrate chemistry and biochemistry, 2010 - Elsevier
From the authors' opinion, this chapter constitutes a modest extension of the seminal and
inspiring contribution of Stowell and Lee on neoglycoconjugates published in this series [CP …

Multivalent glycoconjugate syntheses and applications using aromatic scaffolds

YM Chabre, R Roy - Chemical Society Reviews, 2013 - pubs.rsc.org
Glycan–protein interactions are of utmost importance in several biological phenomena.
Although the variety of carbohydrate residues in mammalian cells is limited to less than a …