MicroRNAs (miRNAs) are short non-coding RNAs that inhibit the expression of target genes
by directly binding to their mRNAs. miRNAs are transcribed as precursor molecules, which …

In recent years, the link between regulatory microRNAs (miRNAs) and diseases has been
the object of intensive research. miRNAs have emerged as key mediators of metabolic …

During microRNA (miRNA) biogenesis, two endonucleolytic reactions convert stem-loop-
structured precursors into mature miRNAs. These processing steps can be …

Currently, non-communicable diseases (NCDs) have emerged as potential risks for humans
due to adopting a sedentary lifestyle and inaccurate diagnoses. The early detection of NCDs …

microRNAs are endogenous small regulatory RNAs that modulate myriad biological
processes by repressing target gene expression in a sequence-specific manner. Here we …

The DNA damage response is mediated by both DNA repair proteins and epigenetic
markers. Here, we observe that N6-methyladenosine (m6A), a mark of the epitranscriptome …

Stress can be temporary or chronic, and mild or acute. Depending on its extent and severity,
cells either alter their metabolism, and adopt a new state, or die. Fluctuations in …

Abstract Photoactivatable-Ribonucleoside-Enhanced Crosslinking and Immunoprecipitation
(PAR-CLIP) in combination with next-generation sequencing is a powerful method for …

Circular RNAs (circRNAs) are widely expressed in eukaryotes. However, only a subset has
been functionally characterized. We identify and validate a collection of circRNAs in …

Non-coding RNA sequences outnumber the protein-coding genes in the human genome,
however our knowledge of their functions is still limited. RNA-binding proteins follow the …