Long-term survival rates after a diagnosis of breast cancer are steadily rising. This is good
news, but clinicians must also recognize that this brings new challenges to the medical …

Background. Oral antineoplastic therapies not only improve survival but also reduce the
burden of care for patients. Yet patients and clinicians face new challenges in managing …

Purpose To examine the impact of marital status on stage at diagnosis, use of definitive
therapy, and cancer-specific mortality among each of the 10 leading causes of cancer …

Background As trials of 5 years of tamoxifen in early breast cancer mature, the relevance of
hormone receptor measurements (and other patient characteristics) to long-term outcome …

Importance Adjuvant chemotherapy improves outcomes of patients with breast cancer.
However, the optimal timing of chemotherapy initiation is unknown. Delayed administration …

Background A number of studies have shown poorer survival among cancer patients with
comorbidity. Several mechanisms may underlie this finding. In this review we summarize the …

Adjuvant hormonal therapy significantly improves long-term survival of breast cancer
patients with hormone receptor-positive disease. Despite the proven clinical efficacy of …

Despite the benefit of adjuvant hormonal therapy (HT) on mortality among women with
breast cancer (BC), many women are non-adherent with its use. We investigated the effects …

Purpose While studies have found that adjuvant hormonal therapy for hormone-sensitive
breast cancer (BC) dramatically reduces recurrence and mortality, adherence to medications …

Purpose To investigate adherence to endocrine treatment and its relationship with disease-
free survival (DFS) in the Breast International Group (BIG) 1-98 clinical trial. Methods The …