Candida albicans Antifungal Resistance and Tolerance in Bloodstream Infections: The Triad Yeast-Host-Antifungal

S Costa-de-Oliveira, AG Rodrigues - Microorganisms, 2020 - mdpi.com
Candida albicans represents the most frequent isolated yeast from bloodstream infections.
Despite the remarkable progress in diagnostic and therapeutic approaches, these infections …

Regulatory circuitry governing fungal development, drug resistance, and disease

RS Shapiro, N Robbins, LE Cowen - Microbiology and molecular …, 2011 - Am Soc Microbiol
Pathogenic fungi have become a leading cause of human mortality due to the increasing
frequency of fungal infections in immunocompromised populations and the limited …

[KNIHA][B] Geomicrobiology

HL Ehrlich, DK Newman - 2008 - taylorfrancis.com
Uncovers the Key Role Microbes Play in the Transformation of Oxidizable and Reducible
MineralsMany areas of geomicrobial processes are receiving serious attention from …

Efflux-mediated antifungal drug resistance

RD Cannon, E Lam**, AR Holmes… - Clinical microbiology …, 2009 - Am Soc Microbiol
Fungi cause serious infections in the immunocompromised and debilitated, and the
incidence of invasive mycoses has increased significantly over the last 3 decades. Slow …

Environmental Sensing and Signal Transduction Pathways Regulating Morphopathogenic Determinants of Candida albicans

S Biswas, P Van Dijck, A Datta - Microbiology and molecular …, 2007 - Am Soc Microbiol
Candida albicans is an opportunistic fungal pathogen that is found in the normal
gastrointestinal flora of most healthy humans. However, under certain environmental …

Candida albicans targets that potentially synergize with fluconazole

H Lu, M Shrivastava, M Whiteway… - Critical reviews in …, 2021 - Taylor & Francis
Fluconazole has characteristics that make it widely used in the clinical treatment of C.
albicans infections. However, fluconazole has only a fungistatic activity in C. albicans …

An update on antifungal targets and mechanisms of resistance in Candida albicans

RA Akins - Medical mycology, 2005 - academic.oup.com
Much progress has been made in the last decade in identifying genes responsible for
antifungal resistance in Candida albicans. Attention has focused on five major C. albicans …

Regulation of multidrug resistance in pathogenic fungi

J Morschhäuser - Fungal Genetics and Biology, 2010 - Elsevier
Infections by opportunistic pathogenic fungi, especially Candida species, Cryptococcus
neoformans, and Aspergillus fumigatus, are a serious medical problem in …

Stress, drugs, and evolution: the role of cellular signaling in fungal drug resistance

LE Cowen, WJ Steinbach - Eukaryotic cell, 2008 - Am Soc Microbiol
The survival of all organisms depends critically upon interactions with the environment,
mediated largely through the action of small molecules. Small molecules can provide the …

Candida albicans drug resistance–another way to cope with stress

RD Cannon, E Lam**, AR Holmes, K Niimi… - …, 2007 - microbiologyresearch.org
There are relatively few classes of antifungal drugs. This restricts clinicians' therapeutic
choices and these choices are further reduced by the emergence of drug resistance …