Antibody–drug conjugates (ADCs) typically require internalisation into cancer cells to
release their cytotoxic payload. However, this places stringent constraints on therapeutic …

Nanoparticles have increasingly been used for a variety of applications, most notably for the
delivery of therapeutic and diagnostic agents. A large number of nanoparticle drug delivery …

Peptide and protein PEGylation is usually undertaken to improve the biopharmaceutical
properties of these drugs and, to date, several examples of conjugates with long …

The term PEGylation describes the modification of biological molecules by covalent
conjugation with polyethylene glycol (PEG), a non-toxic, non-immunogenic polymer, and is …

After intravenous (iv) injection of 125 I-labeled poly (ethylene glycol)(PEG) with different
molecular weights to mice, the radioactivity of the organs was measured to …

Although, the drug delivery system (DDS) concept is not new, great progress has recently
been made in the treatment of a variety of diseases. Targeting delivery of drugs to the …

Despite recent advances in the diagnosis and treatment of breast cancer (BC), it remains a
global health issue affecting millions of women annually. Poor prognosis in BC patients is …

The development of drug delivery systems using nanoparticles as carriers for small and
large therapeutic molecules remains a rapidly growing area of research. The advantages of …

In recent years, various nanomaterials have emerged as an exciting tool in cancer
theranostic applications due to their multifunctional property and intrinsic molecular property …

The overview covers the discovery of N-(2-hydroxypropyl) methacrylamide (HPMA)
copolymers, initial studies on their synthesis, evaluation of biological properties, and …