Artificial intelligence in cancer target identification and drug discovery
Artificial intelligence is an advanced method to identify novel anticancer targets and discover
novel drugs from biology networks because the networks can effectively preserve and …
novel drugs from biology networks because the networks can effectively preserve and …
Recovering dynamic networks in big static datasets
R Wu, L Jiang - Physics Reports, 2021 - Elsevier
The promise of big data is enormous and nowhere is it more critical than in its potential to
contain important, undiscovered interdependence among thousands of variables. Networks …
contain important, undiscovered interdependence among thousands of variables. Networks …
Assessment of network module identification across complex diseases
Many bioinformatics methods have been proposed for reducing the complexity of large gene
or protein networks into relevant subnetworks or modules. Yet, how such methods compare …
or protein networks into relevant subnetworks or modules. Yet, how such methods compare …
Characterizing the fuzzy community structure in link graph via the likelihood optimization
Detecting fuzzy communities in networks is a critical but challenging task in many fields
including biology, technology, social system and so on. Current technology is largely reliant …
including biology, technology, social system and so on. Current technology is largely reliant …
Modularity in biological networks
Network modeling, from the ecological to the molecular scale has become an essential tool
for studying the structure, dynamics and complex behavior of living systems. Graph …
for studying the structure, dynamics and complex behavior of living systems. Graph …
Community detection in complex networks using stacked autoencoders and crow search algorithm
The presence of community structures in complex networks reveals meaningful insights
about such networks and their constituent entities. Finding groups of related nodes based on …
about such networks and their constituent entities. Finding groups of related nodes based on …
ClonoCluster: a method for using clonal origin to inform transcriptome clustering
Clustering cells based on their high-dimensional profiles is an important data reduction
process by which researchers infer distinct cellular states. The advent of cellular barcoding …
process by which researchers infer distinct cellular states. The advent of cellular barcoding …
Inferring functional communities from partially observed biological networks exploiting geometric topology and side information
Cellular biological networks represent the molecular interactions that shape function of living
cells. Uncovering the organization of a biological network requires efficient and accurate …
cells. Uncovering the organization of a biological network requires efficient and accurate …
A novel strategy for decoding and validating the combination principles of huanglian jiedu decoction from multi-scale perspective
KX Wang, Y Gao, WX Gong, XF Ye, LY Fan… - Frontiers in …, 2020 - frontiersin.org
Traditional Chinese medicine (TCM) formulas treat complex diseases through combined
botanical drugs which follow specific compatibility rules to reduce toxicity and increase …
botanical drugs which follow specific compatibility rules to reduce toxicity and increase …
[HTML][HTML] A new feature selection method based on feature distinguishing ability and network influence
Y Qi, B Su, X Lin, H Zhou - Journal of Biomedical Informatics, 2022 - Elsevier
The occurrence and development of diseases are related to the dysfunction of biomolecules
(genes, metabolites, etc.) and the changes of molecule interactions. Identifying the key …
(genes, metabolites, etc.) and the changes of molecule interactions. Identifying the key …