[HTML][HTML] Fusion genes in pancreatic tumors

A Gkountakos, AD Singhi, CB Westphalen, A Scarpa… - Trends in Cancer, 2024 - cell.com
Gene fusions and rearrangements play a crucial role in tumor biology. They are rare events
typically detected in KRAS wild-type (WT) pancreatic tumors. Their identification can inform …

A narrative review on rare types of pancreatic cancer: should they be treated as pancreatic ductal adenocarcinomas?

VHF de Jesus, MDS Donadio… - Therapeutic …, 2024 - journals.sagepub.com
Pancreatic cancer is one of the deadliest malignancies in humans and it is expected to play
a bigger part in cancer burden in the years to come. Pancreatic ductal adenocarcinoma …

Histological variants of pancreatic ductal adenocarcinoma: a survival analysis

A Bengtsson, R Andersson, D Ansari - Langenbeck's Archives of Surgery, 2024 - Springer
Purpose Pancreatic ductal adenocarcinoma (PDAC) can be classified into distinct
histological subtypes based on the WHO nomenclature. The aim of this study was to …

Genomic determinants of biological aggressiveness and poor prognosis of pancreatic cancers: KRAS and beyond

C Ciulla, C Luchini - Expert Review of Molecular Diagnostics, 2024 - Taylor & Francis
Introduction A marked histomolecular heterogeneity characterizes pancreatic cancer. Thus,
different tumor histologies with divergent genomic profiles exist within the same category …

Diagnostic Pearls and Pitfalls in the Evaluation of Biopsies of the Pancreas

C Luchini - Archives of Pathology & Laboratory Medicine, 2024 - meridian.allenpress.com
Context.—The examination of small pancreatic biopsies is a difficult task for pathologists.
This is due to the scant and fragmented material often obtained from diagnostic procedures …

[HTML][HTML] Invasive lobular carcinoma metastasis to pancreas mimicking pancreatic signet ring cell carcinoma: A case report and systematic review of the literature

C Rossi, A Gallotti, A Messina, L Cobianchi… - … -Research and Practice, 2024 - Elsevier
Metastasis to the gastrointestinal tract is a rare instance in the natural history of breast
cancer, usually in association with lobular histology and widespread dissemination of …

Long-Term Survivor of Intrahepatic Cholangiocarcinoma for over 18 Years: Case Study with Longitudinal Histo-molecular and Tumor Immune Microenvironment …

P Mattiolo, M De Bellis, A Mafficini, M Fassan… - Journal of …, 2024 - Springer
Background Intrahepatic cholangiocarcinoma is a biliary neoplasm usually showing a
dismal prognosis. In early stages, surgical resection is the best treatment option, significantly …