Graph representation learning in biomedicine and healthcare

MM Li, K Huang, M Zitnik - Nature Biomedical Engineering, 2022 - nature.com
Networks—or graphs—are universal descriptors of systems of interacting elements. In
biomedicine and healthcare, they can represent, for example, molecular interactions …

[HTML][HTML] From traditional ethnopharmacology to modern natural drug discovery: A methodology discussion and specific examples

S Pirintsos, A Panagiotopoulos, M Bariotakis… - Molecules, 2022 - mdpi.com
Ethnopharmacology, through the description of the beneficial effects of plants, has provided
an early framework for the therapeutic use of natural compounds. Natural products, either in …

Network-based drug repurposing for novel coronavirus 2019-nCoV/SARS-CoV-2

Y Zhou, Y Hou, J Shen, Y Huang, W Martin, F Cheng - Cell discovery, 2020 - nature.com
Human coronaviruses (HCoVs), including severe acute respiratory syndrome coronavirus
(SARS-CoV) and 2019 novel coronavirus (2019-nCoV, also known as SARS-CoV-2), lead …

[HTML][HTML] Investigation of Some Antiviral N-Heterocycles as COVID 19 Drug: Molecular Docking and DFT Calculations

M Hagar, HA Ahmed, G Aljohani… - International Journal of …, 2020 - mdpi.com
The novel coronavirus, COVID-19, caused by SARS-CoV-2, is a global health pandemic that
started in December 2019. The effective drug target among coronaviruses is the main …

[HTML][HTML] A network medicine approach to investigation and population-based validation of disease manifestations and drug repurposing for COVID-19

Y Zhou, Y Hou, J Shen, R Mehra, A Kallianpur… - PLoS …, 2020 - journals.plos.org
The global coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), has led to unprecedented social and …

[HTML][HTML] A comprehensive review of artificial intelligence and network based approaches to drug repurposing in Covid-19

F Ahmed, AM Soomro, ARC Salih… - Biomedicine & …, 2022 - Elsevier
Conventional drug discovery and development is tedious and time-taking process; because
of which it has failed to keep the required pace to mitigate threats and cater demands of viral …

[HTML][HTML] A comprehensive review of integrative pharmacology-based investigation: A paradigm shift in traditional Chinese medicine

H Xu, Y Zhang, P Wang, J Zhang, H Chen… - … Pharmaceutica Sinica B, 2021 - Elsevier
Over the past decade, traditional Chinese medicine (TCM) has widely embraced systems
biology and its various data integration approaches to promote its modernization. Thus …

A critical review of machine learning algorithms in maritime, offshore, and oil & gas corrosion research: A comprehensive analysis of ANN and RF models

MMH Imran, S Jamaludin, AFM Ayob - Ocean Engineering, 2024 - Elsevier
Corrosion presents significant challenges in the marine, offshore, and oil and gas industries,
resulting in annual economic losses amounting to billions of dollars. To address these …

Defining disease-related modules based on weighted miRNA synergistic network

C Li, P Dou, T Wang, X Lu, G Xu, X Lin - Computers in Biology and …, 2023 - Elsevier
MicroRNAs (miRNAs) play an important role in the biological process. Their expression and
functional changes have been observed in most cancers. Meanwhile, there exists …

Markovian approach to tackle competing pathogens in simplicial complex

Y Nie, W Li, L Pan, T Lin, W Wang - Applied Mathematics and Computation, 2022 - Elsevier
Recent studies on network spreading dynamics often adopt pairwise interaction to describe
the simple spreading process while using higher-order interaction to describe the collective …