Metal–organic frameworks as solid catalysts for the synthesis of nitrogen-containing heterocycles

A Dhakshinamoorthy, H Garcia - Chemical Society Reviews, 2014 - pubs.rsc.org
Metal–organic frameworks (MOFs) are finding increasing application as solid catalysts for
liquid phase reactions leading to the synthesis of fine chemicals. In the present review we …

Naphtho [2, 1-b] furan derived triazole-pyrimidines as highly potential InhA and Cytochrome c peroxidase inhibitors: synthesis, DFT calculations, drug-likeness profile …

DL Roopa, K Shyamsunder, P Karunakar… - Journal of Molecular …, 2023 - Elsevier
Napthofuran and its fused heterocyclic derivatives evaluated with varied biological activity
functional groups comprise an important class of compounds for new chemical entities. We …

Review on synthetic approaches towards barbituric acids‐based furo[2,3‐d]pyrimidines

A Olyaei, M Sadeghpour - Journal of Heterocyclic Chemistry, 2023 - Wiley Online Library
Pyrimidine annulated five‐membered heterocyclic scaffolds containing oxygen as
furopyrimidine, particularly furo [2, 3‐d] pyrimidine derivatives are an important class of …

[PDF][PDF] Synthesis and antimicrobial evaluation of some new thienopyrimidine derivatives

MH Bhuiyan, KM Rahman, K Hossain… - ACTA …, 2006 - core.ac.uk
Reaction of heteroaromatic o-aminonitrile with ethyl N--[bis (methylthio) methylene] amino
acetate resulted in annelation of a thieno [3, 2-e] imidazo [1, 2-c] pyrimidine moiety in a one …

[PDF][PDF] Antibacterial, antifungal and antiviral activities of pyrimido [4, 5-d] pyrimidine derivatives through computational approaches

A Kumer, ME Kobir, M Alam, U Chakma, P Akter… - Org …, 2022 - researchgate.net
Pyrimido [4, 5-d] pyrimidine conveys antimicrobial activity against various micro pathogens
having functionalized properties. As a result, this study has designed to illustrate the …

Synthetic utility of bifunctional thiophene derivatives and antimicrobial evaluation of the newly synthesized agents

AA Abu-Hashem, KM Abu-Zied… - Monatshefte für Chemie …, 2011 - Springer
The key intermediate ethyl 2-amino-5-benzoyl-4-methylthiophene-3-carboxylate was
prepared by a Gewald reaction starting from benzoylacetone, sulfur, and ethyl cyanoacetate …

Metal-organic framework Cu3 (BTC) 2 (H2O) 3 catalyzed Aldol synthesis of pyrimidine-chalcone hybrids

NB Pathan, AM Rahatgaonkar… - Catalysis Communications, 2011 - Elsevier
A typical metal organic framework,[Cu 3 (BTC) 2 (H 2 O) 3, BTC= 1, 3, 5-benzene
tricarboxylate] has been used for the synthesis of pyrimidine-chalcones. We have explored a …

One-pot three component isocyanide-based reaction: Synthesis of novel tetracyclic fused furo [2′, 3′: 4, 5] pyrimido [2, 1-b][1, 3] benzothiazole

M Zangouei, AA Esmaeili, JT Mague - Tetrahedron, 2017 - Elsevier
A rapid, efficient and benign protocol has been developed for the construction of potentially
biologically active furo [2′, 3′: 4, 5] pyrimido [2, 1-b][1, 3] benzothiazole derivatives as …

[HTML][HTML] Furo [2, 3-d] pyrimidine based derivatives as kinase inhibitors and anticancer agents

MA Aziz, RAT Serya, DS Lasheen… - Future Journal of …, 2016 - Elsevier
Furopyrimidines are fused heterocyclic ring systems. Structurally, they are bioisoteres to
purines and exerting pharmacological actions in various aspects. They are known to play an …

Furan- and Furopyrimidine-Based Derivatives: Synthesis, VEGFR-2 Inhibition, and In Vitro Cytotoxicity

AH Abd El-Haleem, MAE Kassem… - ACS Medicinal …, 2024 - ACS Publications
New derivatives 4a–d, 6, 7a–d, 8a–c, 9, 11a, 11b, 12a–f, 13a–c, and 14 were synthesized
and evaluated for their VEGFR-2 inhibition. Compounds 4c, 7b, and 7c showed remarkable …