Adrenal insufficiency (AI) is a condition characterized by an absolute or relative deficiency of
adrenal cortisol production. Primary AI (PAI) is rare and is caused by direct adrenal failure …

Objective: To formulate clinical practice guidelines for hormonal replacement in
hypopituitarism in adults. Participants: The participants include an Endocrine Society …

Sheehan syndrome (SS) caused by postpartum hemorrhage leads to partial or complete
pituitary hormone deficiency. In addition to lipid and glucose abnormalities, patients with SS …

Objective Adrenal insufficiency (AI) is characterized by increased mortality compared to
general population, mainly due to cardiovascular disease. Conventional glucocorticoid (GC) …

Adrenal insufficiency is defined as impaired adrenocortical hormone synthesis. According to
its source, the deficit is classified as primary (adrenal steroidogenesis impairment) …

The Endocrine Society Guidelines and recent reviews of adrenal insufficiency (AI)
recommend a daily glucocorticoid replacement dose of 15 to 25 mg with a midpoint of 20 mg …

Introduction Patients who need glucocorticoid replacement in both primary and secondary
adrenal insufficiency (AI) have the choice of either once-daily prednisolone or thrice-daily …

Background Dual-release hydrocortisone (DR-HC) improves metabolism in patients with
adrenal insufficiency. The aims of this study were to compare the cardiovascular and …

There is an increased mortality associated with adrenal insufficiency despite glucocorticoid
replacement therapy with a standardized mortality ratio greater than two. The cause of the …

Glucocorticoid deficiency is the clinical state characterised by inadequate cortisol
production. It may occur due to the primary failure of the adrenal cortex or to lack of …