Multiple signaling pathways in Sertoli cells: recent findings in spermatogenesis
FD Ni, SL Hao, WX Yang - Cell death & disease, 2019 - nature.com
The functions of Sertoli cells in spermatogenesis have attracted much more attention
recently. Normal spermatogenesis depends on Sertoli cells, mainly due to their influence on …
recently. Normal spermatogenesis depends on Sertoli cells, mainly due to their influence on …
Improvement effect of metformin on female and male reproduction in endocrine pathologies and its mechanisms
AO Shpakov - Pharmaceuticals, 2021 - mdpi.com
Metformin (MF), a first-line drug to treat type 2 diabetes mellitus (T2DM), alone and in
combination with other drugs, restores the ovarian function in women with polycystic ovary …
combination with other drugs, restores the ovarian function in women with polycystic ovary …
Comparative overview of the mechanisms of action of hormones and endocrine disruptor compounds
Y Combarnous, TMD Nguyen - Toxics, 2019 - mdpi.com
Endocrine Disruptor Compounds (EDCs) are synthetic or natural molecules in the
environment that promote adverse modifications of endogenous hormone regulation in …
environment that promote adverse modifications of endogenous hormone regulation in …
Environmental estrogen exposure converts lipid metabolism in male fish to a female pattern mediated by AMPK and mTOR signaling pathways
SX Sun, JL Wu, HB Lv, HY Zhang, J Zhang… - Journal of Hazardous …, 2020 - Elsevier
Environmental estrogens, including bisphenol A (BPA) and 17β-estradiol (E2), which are
widely used in industries and medicine, pose a severe ecological threat to fish due to …
widely used in industries and medicine, pose a severe ecological threat to fish due to …
Bacterial infections affect male fertility: A focus on the oxidative stress-autophagy axis
S Wang, K Zhang, Y Yao, J Li, S Deng - Frontiers in Cell and …, 2021 - frontiersin.org
Numerous factors trigger male infertility, including lifestyle, the environment, health, medical
resources and pathogenic microorganism infections. Bacterial infections of the male …
resources and pathogenic microorganism infections. Bacterial infections of the male …
[HTML][HTML] Ginkgo biloba extract (EGb 761) mitigates methotrexate-induced testicular insult in rats: Targeting oxidative stress, energy deficit and spermatogenesis
DF Mansour, DO Saleh, OA Ahmed-Farid… - Biomedicine & …, 2021 - Elsevier
Methotrexate (MTX) is commonly used as a therapeutic agent in the treatment of
malignancies and autoimmune disorders. Risk of subsequent infertility following MTX …
malignancies and autoimmune disorders. Risk of subsequent infertility following MTX …
[HTML][HTML] The effect of Nigella sativa oil and metformin on male seminal parameters and testosterone in Wistar rats exposed to an obesogenic diet
K Leisegang, W Almaghrawi, R Henkel - Biomedicine & pharmacotherapy, 2021 - Elsevier
Obesity is a significant global health and socio-economic challenge, and considered an
important risk factor for poor health outcomes including male reproductive dysfunction and …
important risk factor for poor health outcomes including male reproductive dysfunction and …
Stimulation of autophagy by dapagliflozin mitigates cadmium-induced testicular dysfunction in rats: the role of AMPK/mTOR and SIRT1/Nrf2/HO-1 pathways
HH Arab, EM Fikry, SE Alsufyani, AM Ashour… - Pharmaceuticals, 2023 - mdpi.com
Cadmium (Cd) is a widespread environmental pollutant that triggers testicular dysfunction.
Dapagliflozin is a selective sodium-glucose co-transporter-2 inhibitor with notable …
Dapagliflozin is a selective sodium-glucose co-transporter-2 inhibitor with notable …
Fisetin ameliorates oxidative glutamate testicular toxicity in rats via central and peripheral mechanisms involving SIRT1 activation
FH Rizk, NA Soliman, SE Abo-Elnasr… - Redox …, 2022 - Taylor & Francis
Objectives This study aimed to evaluate the potential mitigating effect of fisetin on
monosodium glutamate (MSG)-induced testicular toxicity and investigate the possible …
monosodium glutamate (MSG)-induced testicular toxicity and investigate the possible …
Quantitative phosphoproteomics analyses reveal the regulatory mechanisms related to frozen-thawed sperm capacitation and acrosome reaction in yak (Bos …
R Zhang, C Liang, X Guo, P Bao, J Pei, F Wu… - Frontiers in …, 2022 - frontiersin.org
Mammalian spermatozoa are not mature after ejaculation and must undergo additional
functional and structural changes within female reproductive tracts to achieve subsequent …
functional and structural changes within female reproductive tracts to achieve subsequent …