CSF amino acid profiles in ICV‐streptozotocin‐induced sporadic Alzheimer's disease in male Wistar rat: a metabolomics and systems biology perspective

A Barzegar Behrooz, H Latifi‐Navid, J Lotfi… - FEBS Open …, 2024 - Wiley Online Library
Alzheimer's disease (AD) is an increasingly important public health concern due to the
increasing proportion of older individuals within the general population. The impairment of …

[PDF][PDF] Autophagy unveiled: New horizons in health and disease

P Mokarram, S Ghavami - … Acta (BBA)-Molecular Basis of Disease, 2024 - researchgate.net
Macroautophagy (hereafter autophagy) plays a crucial role in maintaining cellular
homeostasis by degrading and recycling damaged cellular components (1, 2). In health …

[HTML][HTML] Lipidomics-driven drug discovery and delivery strategies in glioblastoma

X Weng, M Gonzalez, J Angelia, S Piroozmand… - … et Biophysica Acta (BBA …, 2025 - Elsevier
With few viable treatment options, glioblastoma (GBM) is still one of the most aggressive and
deadly types of brain cancer. Recent developments in lipidomics have demonstrated the …

[PDF][PDF] Multi-Target Directed Ligands and Lipidomics Approach for Glioblastoma Drug Discovery

S Pecic, X Weng, MGA Emami, AB Behrooz… - researchgate.net
Traditional medicinal chemistry has focused on single-target drugs, effective for many
conditions but inadequate for complex diseases like cancer. Polytherapy tackles this but …