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Intra‐operative analgesia with remifentanil vs. dexmedetomidine: a systematic review and meta‐analysis with trial sequential analysis
S Grape, KR Kirkham, J Frauenknecht… - Anaesthesia, 2019 - Wiley Online Library
Intra‐operative remifentanil is associated with increased postoperative analgesic
requirements and opioid consumption. Dexmedetomidine has characteristics suggesting it …
requirements and opioid consumption. Dexmedetomidine has characteristics suggesting it …
[HTML][HTML] Opioid-free anesthesia benefit–risk balance: a systematic review and meta-analysis of randomized controlled trials
A Salomé, H Harkouk, D Fletcher… - Journal of clinical medicine, 2021 - mdpi.com
Opioid-free anesthesia (OFA) is used in surgery to avoid opioid-related side effects.
However, uncertainty exists in the balance between OFA benefits and risks. We searched for …
However, uncertainty exists in the balance between OFA benefits and risks. We searched for …
Opioid-free total intravenous anesthesia with propofol, dexmedetomidine and lidocaine infusions for laparoscopic cholecystectomy: a prospective, randomized, double …
BACKGROUND AND OBJECTIVES: Intraoperative use of opioids may be associated with
postoperative hyperalgesia and increased analgesic consumption. Side effects due to …
postoperative hyperalgesia and increased analgesic consumption. Side effects due to …
Pharmacology of sedative-analgesic agents: dexmedetomidine, remifentanil, ketamine, volatile anesthetics, and the role of peripheral mu antagonists
Dexmedetomidine is a highly selective alpha-2 agonist that provides anxiolysis and
cooperative sedation without respiratory depression. It decreases central nervous system …
cooperative sedation without respiratory depression. It decreases central nervous system …
An updated focused review of dexmedetomidine in adults
Objective: To evaluate recent comparative studies regarding the safety and efficacy of
dexmedetomidine in adults. Data Sources: Articles evaluating safety and efficacy of …
dexmedetomidine in adults. Data Sources: Articles evaluating safety and efficacy of …
Is intraoperative dexmedetomidine a new option for postoperative pain treatment? A meta-analysis of randomized controlled trials
In the present meta-analysis, we assessed the efficacy and safety of intravenous
administration of dexmedetomidine (DEX) compared with placebo or opioids for acute …
administration of dexmedetomidine (DEX) compared with placebo or opioids for acute …
The effect of intraoperative dexmedetomidine on postoperative analgesia and sedation in pediatric patients undergoing tonsillectomy and adenoidectomy
OA Olutoye, CD Glover, JW Diefenderfer… - Anesthesia & …, 2010 - journals.lww.com
BACKGROUND: The immediate postoperative period after tonsillectomy and
adenoidectomy, one of the most common pediatric surgical procedures, is often difficult …
adenoidectomy, one of the most common pediatric surgical procedures, is often difficult …
Dexmedetomidine versus remifentanil in postoperative pain control after spinal surgery: a randomized controlled study
W Hwang, J Lee, J Park, J Joo - BMC anesthesiology, 2015 - Springer
Background Total intravenous anesthesia (TIVA) is used widely in spinal surgery because
inhalational anesthetics are known to decrease the amplitude of motor evoked potentials …
inhalational anesthetics are known to decrease the amplitude of motor evoked potentials …
Dexmedetomidine combined with general anesthesia provides similar intraoperative stress response reduction when compared with a combined general and epidural …
BACKGROUND: Epidural anesthesia may attenuate the sympathetic hyperactivity and stress
response from surgery. In this study, we compared the stress response, hemodynamic …
response from surgery. In this study, we compared the stress response, hemodynamic …
Effect of intravenous infusion of dexmedetomidine on perioperative haemodynamic changes and postoperative recovery: A study with entropy analysis
CR Patel, SR Engineer, BJ Shah… - Indian journal of …, 2012 - journals.lww.com
Background: Dexmedetomidine, an α2 agonist, when used as an adjuvant in general
anaesthesia attenuates stress response to various noxious stimuli, maintains perioperative …
anaesthesia attenuates stress response to various noxious stimuli, maintains perioperative …