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Type 2 diabetes and its impact on the immune system
Introduction: Type 2 Diabetes (T2D) is a major health problem worldwide. This metabolic
disease is indicated by high blood glucose levels due to insufficient insulin production by the …
disease is indicated by high blood glucose levels due to insufficient insulin production by the …
Methylenetetrahydrofolate (MTHFR), the one-carbon cycle, and cardiovascular risks
The 5-10-methylenetetrahydrofolate reductase (MTHFR) enzyme is vital for cellular
homeostasis due to its key functions in the one-carbon cycle, which include methionine and …
homeostasis due to its key functions in the one-carbon cycle, which include methionine and …
[HTML][HTML] The interaction among gut microbes, the intestinal barrier and short chain fatty acids
J Ma, X Piao, S Mahfuz, S Long, J Wang - Animal Nutrition, 2022 - Elsevier
The mammalian gut is inhabited by a massive and complicated microbial community, in
which the host achieves a stable symbiotic environment through the interdependence …
which the host achieves a stable symbiotic environment through the interdependence …
Gut microbiota as a trigger for metabolic inflammation in obesity and type 2 diabetes
TPM Scheithauer, E Rampanelli, M Nieuwdorp… - Frontiers in …, 2020 - frontiersin.org
The gut microbiota has been linked to the development of obesity and type 2 diabetes (T2D).
The underlying mechanisms as to how intestinal microbiota may contribute to T2D are only …
The underlying mechanisms as to how intestinal microbiota may contribute to T2D are only …
Antioxidant effects and mechanisms of medicinal plants and their bioactive compounds for the prevention and treatment of type 2 diabetes: an updated review
Diabetes mellitus is a metabolic disorder that majorly affects the endocrine gland, and it is
symbolized by hyperglycemia and glucose intolerance owing to deficient insulin secretory …
symbolized by hyperglycemia and glucose intolerance owing to deficient insulin secretory …
Mechanisms of inflammatory responses and development of insulin resistance: how are they interlinked?
Background Insulin resistance (IR) is one of the major hallmark for pathogenesis and
etiology of type 2 diabetes mellitus (T2DM). IR is directly interlinked with various …
etiology of type 2 diabetes mellitus (T2DM). IR is directly interlinked with various …
[HTML][HTML] Role of c-Jun N-terminal kinase (JNK) in obesity and type 2 diabetes
JHM Yung, A Giacca - Cells, 2020 - mdpi.com
Obesity has been described as a global epidemic and is a low-grade chronic inflammatory
disease that arises as a consequence of energy imbalance. Obesity increases the risk of …
disease that arises as a consequence of energy imbalance. Obesity increases the risk of …
Mechanistic links between obesity, diabetes, and blood pressure: role of perivascular adipose tissue
SN Saxton, BJ Clark, SB Withers… - Physiological …, 2019 - journals.physiology.org
Obesity is increasingly prevalent and is associated with substantial cardiovascular risk.
Adipose tissue distribution and morphology play a key role in determining the degree of …
Adipose tissue distribution and morphology play a key role in determining the degree of …
[HTML][HTML] Lipid signaling and lipotoxicity in metaflammation: indications for metabolic disease pathogenesis and treatment
ME Ertunc, GS Hotamisligil - Journal of lipid research, 2016 - Elsevier
Lipids encompass a wide variety of molecules such as fatty acids, sterols, phospholipids,
and triglycerides. These molecules represent a highly efficient energy resource and can act …
and triglycerides. These molecules represent a highly efficient energy resource and can act …
Diabetes mellitus and inflammation
Type 2 diabetes mellitus (T2DM) is increasingly common worldwide. Related complications
account for increased morbidity and mortality, and enormous healthcare spending …
account for increased morbidity and mortality, and enormous healthcare spending …