Screening Techniques for Drug Discovery in Alzheimer's Disease

S Maniam, S Maniam - ACS omega, 2024 - ACS Publications
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by progressive and
irreversible impairment of memory and other cognitive functions of the aging brain …

A bibliometric and visual analysis of epigenetic research publications for Alzheimer's disease (2013–2023)

YP Zhao, WJ Ai, JF Zheng, XL Hu… - Frontiers in Aging …, 2024 - frontiersin.org
Background Currently, the prevalence of Alzheimer's disease (AD) is progressively rising,
particularly in developed nations. There is an escalating focus on the onset and progression …

Association of vitamin B2 intake with cognitive performance in older adults: a cross-sectional study

L Zhou - Journal of Translational Medicine, 2023 - Springer
Background To scrutinize the relationship between vitamin B2 consumption and cognitive
function based on the NHANES database. Methods This cross-sectional study included …

Restoration of epigenetic impairment in the skeletal muscle and chronic inflammation resolution as a therapeutic approach in sarcopenia

G Livshits, A Kalinkovich - Ageing Research Reviews, 2024 - Elsevier
Sarcopenia is an age-associated loss of skeletal muscle mass, strength, and function,
accompanied by severe adverse health outcomes, such as falls and fractures, functional …

Roseburia intestinalis Supplementation Could Reverse the Learning and Memory Impairment and m6A Methylation Modification Decrease Caused by 27 …

X Sun, C Zhou, M Ju, W Feng, Z Guo, C Qi, K Yang… - Nutrients, 2024 - mdpi.com
The abnormality in N6-methyladenosine (m6A) methylation is involved in the course of
Alzheimer's disease (AD), while the intervention of 27-Hydroxycholesterol (27-OHC) can …

Unlocking the Therapeutic Potential of Natural Products for Alzheimer's Disease

Z Li, Z Zhang, B Yu - Journal of Medicinal Chemistry, 2025 - ACS Publications
Alzheimer's disease (AD) is a progressive neurodegenerative condition marked by memory
loss and cognitive decline. With current treatments offering limited effectiveness, researchers …

Exploring the complexities of epigenetics in multiple sclerosis: A study involving meta-analysis of DNA methylation profiles, epigenetic drift, and rare epivariations

GN Baldrighi, R Cavagnola, D Sacco… - Multiple Sclerosis …, 2024 - journals.sagepub.com
Background Multiple sclerosis (MS) is an autoimmune condition characterized by
inflammatory and neurodegenerative traits. Recently, DNA methylation has emerged as a …

Smart drug delivery system of nano-mebendazole medication, which depends on chitosan nanomolecule for murine trichinellosis treatment

AM Henaish, NM Mira, EA Moussa… - Inorganic Chemistry …, 2025 - Elsevier
The primary objective of this study is to formulate a medication system for mebendazole
(MBZ) as an antiparasitic agent by the nanocomposite self-assembly of MBZ with the surface …

[HTML][HTML] Obstructive sleep apnea hypopnea syndrome and vascular lesions: An update on what we currently know

Z Mao, P Zheng, X Zhu, L Wang, F Zhang, H Liu, H Li… - Sleep Medicine, 2024 - Elsevier
Obstructive sleep apnea-hypopnea syndrome (OSAHS) is the most prevalent sleep and
respiratory disorder. This syndrome can induce severe cardiovascular and cerebrovascular …

Mebendazole nano-medication which incorporation nano-chitosan decorated by zinc oxide nanoparticles for intestinal murine trichinellosis through a drug delivery …

AM Henaish, NM Mira, HS Zoghroban… - Journal of Dispersion …, 2024 - Taylor & Francis
The objective is to develop the drug system of mebendazole (MBZ) as an antiparasitic drug
via the self-assembly of MBZ with nano chitosan (Cs) and zinc oxide nanoparticles (ZnO …