After the discovery of zinc deficiency in the 1960s, it soon became clear that zinc is essential
for the function of the immune system. Zinc ions are involved in regulating intracellular …

Zinc metabolism at the cellular level is critical for many biological processes in the body. A
key observation is the disruption of cellular homeostasis, often coinciding with disease …

Zinc is a trace element nutrient that is essential for life. This mineral serves as a cofactor for
enzymes that are involved in critical biochemical processes and it plays many structural …

Background & Aims Pancreatic cancer has the highest prevalence of cancer-associated
cachexia among all cancers. ZIP4 promotes pancreatic cancer progression by regulating …

Glioblastoma multiforme (GBM) is the most malignant and aggressive type of brain tumor
with an average life expectancy of less than 15 months. This is mostly due to the highly …

Pancreatic cancer is one of the deadliest cancers with rapid disease progression. Further
elucidation of its underlying molecular mechanisms and novel biomarkers for early detection …

Zinc is an essential element and serves as a structural or catalytic component in many
proteins. Two families of transporters are involved in maintaining cellular zinc homeostasis …

Zinc (Zn) is an essential micronutrient required for over 300 different cellular processes,
including DNA and protein synthesis, enzyme activity, and intracellular signaling. Cellular Zn …

Abstract Background The zinc transporters Zrt-and Irt-related protein (ZIP/SLC39) are
overexpressed in human tumors and correlate with poor prognosis; however, their …

Zinc is a crucial trace element in the human body, playing a role in various physiological
processes such as oxidative stress, neurotransmission, protein synthesis, and DNA repair …