Proteomic analysis of cells, tissues and body fluids has generated valuable insights into the
complex processes influencing human biology. Proteins represent intermediate phenotypes …

Clinical analysis of blood is the most widespread diagnostic procedure in medicine, and
blood biomarkers are used to categorize patients and to support treatment decisions …

Skyline is a Windows client application for targeted proteomics method creation and
quantitative data analysis. It is open source and freely available for academic and …

Most proteomic studies use liquid chromatography coupled to tandem mass spectrometry to
identify and quantify the peptides generated by the proteolysis of a biological sample …

Proteomics is the field of study that includes the analysis of proteins, from either a basic
science prospective or a clinical one. Proteins can be investigated for their abundance …

Interrogation of the human proteome in a highly multiplexed and efficient manner remains a
coveted and challenging goal in biology. We present a new aptamer-based proteomic …

Selected reaction monitoring (SRM) is a targeted mass spectrometry technique that is
emerging in the field of proteomics as a complement to untargeted shotgun methods. SRM is …

Selected reaction monitoring on a triple quadrupole mass spectrometer is currently
experiencing a renaissance within the proteomics community for its, as yet, unparalleled …

The extracellular matrix (ECM) is a complex meshwork of cross-linked proteins providing
both biophysical and biochemical cues that are important regulators of cell proliferation …

Collision cross section (CCS) measurements resulting from ion mobility–mass spectrometry
(IM-MS) experiments provide a promising orthogonal dimension of structural information in …