A review on recent progress in synthesis and biological activities of thiadiazole and its derivatives

S Ahmad, MZ Alam, U Salma, M Mohasin… - Journal of Molecular …, 2024 - Elsevier
Thiadiazole derivatives, a class of compounds with significant biological applications, are
extensively explored in medicinal chemistry. The synthesis section covers various methods …

[PDF][PDF] Chemistry of 1, 2, 4-triazole: a review article

JK Shneine, YH Alaraji - Spectroscopy, 2016 - researchgate.net
Triazole was first synthesized over a century ago, but still attracts attention of chemists,
biologists, technologists and other specialists. In recent years, antiviral, anti-inflammatory …

Synthesis of Schiff and Mannich bases of new s-triazole derivatives and their potential applications for removal of heavy metals from aqueous solution and as …

ZA Hozien, AFM El-Mahdy, AA Markeb, LSA Ali… - RSC …, 2020 - pubs.rsc.org
An efficient, simple, and one-pot double Mannich reaction was performed for the synthesis of
cyclized 2-methyl-6-substituted-6, 7-dihydro-5H-s-triazolo [5, 1-b]-1, 3, 5-thiadiazines via a …

A brief review article: Various synthesis and therapeutic importance of 1, 2, 4-triazole and its derivatives.

AH MALANI, AH Makwana… - Moroccan Journal of …, 2017 - revues.imist.ma
Heterocyclic compounds play an important part in medicinal chemistry. Different derivatives
of heterocyclic compounds are useful for the various pharmacological activities. Up to till …

Synthesis and antimicrobial activities of some new bis (Schiff Bases) and their triazole-based lariat macrocycles

RM Kassab, FSAM Khalil, AA Abbas - Polycyclic Aromatic …, 2022 - Taylor & Francis
New series of bis (amino-1, 2, 4-triazoles‏) 5a–f were prepared by the reaction of bis (chloro)
diamides 3a–d with 5-substituted-4-amino-1, 2, 4-triazoles-3-thiole (4a–c). Reaction of bis …

Synthetic utility of aminomercapto [1, 2, 4] triazoles in the preparation of fused triazoles

SM Riyadh, TZ Abolibda, AR Sayed… - Current Organic …, 2022 - benthamdirect.com
Triazoles and their fused derivatives are regarded as one of the most pharmacologically
significant pillars due to their potent, broad, and numerous activities. This current review …

[HTML][HTML] Preparation, Antimicrobial Activity and Docking Study of Vanadium Mixed Ligand Complexes Containing 4-Amino-5-hydrazinyl-4H-1,2,4-triazole-3-thiol and …

D Domyati, SA Zabin, AA Elhenawy, M Abdelbaset - Processes, 2021 - mdpi.com
The synthesis of mixed-ligand complexes is considered an important strategy for develo**
new metal complexes of enhanced biological activity. This paper presents the synthesis …

Synthesis, antimicrobial, and antioxidant screening of aryl acetic acid incorporated 1, 2, 4‐triazolo‐1, 3, 4‐thiadiazole derivatives

VK Kamboj, A Kapoor, S Jain - Journal of Heterocyclic …, 2019 - Wiley Online Library
Some novel [1, 2, 4] triazolo [3, 4‐b][1, 3, 4] thiadiazole derivatives were synthesized from
aryl acetic acids. All the synthesized derivatives were selected for the screening of …

Discovery of Dual Inhibitors of Acetyl and Butrylcholinesterase and Antiproliferative Activity of 1, 2, 4‐Triazole‐3‐thiol: Synthesis and In Silico Molecular Study

SZ Siddiqui, M Arfan, MA Abbasi, SAA Shah… - …, 2020 - Wiley Online Library
The aim of this current study is to discover effective acetyl and butrylcholinesterase enzyme
inhibitors. A concise library of S‐alkylated/arylated‐4‐ethyl‐5‐(4‐methoxyphenyl)‐4H‐1, 2 …

Synthesis and antitumor evaluation of novel fused heterocyclic 1, 2, 4-triazolo [3, 4-b]-1, 3, 4-thiadiazole derivatives

XJ Liu, HY Liu, HX Wang, YP Shi, R Tang… - Medicinal Chemistry …, 2019 - Springer
In this study, twenty three 3, 6-disubstituted 1, 2, 4-triazolo [3, 4-b]-1, 3, 4-thiadiazole
derivatives were synthesized and their antiproliferative activities in vitro were studied against …