25th anniversary article: Rational design and applications of hydrogels in regenerative medicine

N Annabi, A Tamayol, JA Uquillas, M Akbari… - Advanced …, 2014 - Wiley Online Library
Hydrogels are hydrophilic polymer‐based materials with high water content and physical
characteristics that resemble the native extracellular matrix. Because of their remarkable …

Thermoresponsive hydrogels in biomedical applications: A seven-year update

L Klouda - European Journal of Pharmaceutics and …, 2015 - Elsevier
Thermally responsive hydrogels modulate their gelation behavior upon temperature change.
Aqueous solutions solidify into hydrogels when a critical temperature is reached. In …

[HTML][HTML] Review of applications and future prospects of stimuli-responsive hydrogel based on thermo-responsive biopolymers in drug delivery systems

S Chatterjee, PC Hui - Polymers, 2021 - mdpi.com
Some of thermo-responsive polysaccharides, namely, cellulose, xyloglucan, and chitosan,
and protein-like gelatin or elastin-like polypeptides can exhibit temperature dependent sol …

Polysaccharide and polypeptide based injectable thermo-sensitive hydrogels for local biomedical applications

HF Darge, AT Andrgie, HC Tsai, JY Lai - International journal of biological …, 2019 - Elsevier
Injectable thermo-responsive hydrogels have been studied for various biomedical
applications including; drug delivery, cell encapsulation, and tissue repairing. There are …

Bioactive injectable hydrogels for on demand molecule/cell delivery and for tissue regeneration in the central nervous system

MA Grimaudo, GS Krishnakumar, E Giusto, F Furlani… - Acta biomaterialia, 2022 - Elsevier
Currently there are no potential curative therapies that can improve the central nervous
system (CNS) regeneration after traumatic injuries or diseases. Indeed, the regeneration of …

Thermogels: In situ gelling biomaterial

SS Liow, Q Dou, D Kai, AA Karim, K Zhang… - ACS Biomaterials …, 2016 - ACS Publications
In situ gel delivery systems are preferred over conventional systems due to sustained and
prolonged release action of therapeutic payload onto the targeted site. Thermogel, a form of …

Harnessing the power of biological macromolecules in hydrogels for controlled drug release in the central nervous system: a review

S Ghosh, S Ghosh, H Sharma, R Bhaskar… - International Journal of …, 2024 - Elsevier
Hydrogels have immense potential in revolutionizing central nervous system (CNS) drug
delivery, improving outcomes for neurological disorders. They serve as promising tools for …

Biomaterial scaffolds in regenerative therapy of the central nervous system

Y Wang, H Tan, X Hui - BioMed research international, 2018 - Wiley Online Library
The central nervous system (CNS) is the most important section of the nervous system as it
regulates the function of various organs. Injury to the CNS causes impairment of …

Hydrogels in spinal cord injury repair strategies

G Perale, F Rossi, E Sundstrom… - ACS chemical …, 2011 - ACS Publications
Nowadays there are at present no efficient therapies for spinal cord injury (SCI), and new
approaches have to be proposed. Recently, a new regenerative medicine strategy has been …

Biopolymer-based strategies in the design of smart medical devices and artificial organs

L Altomare, L Bonetti, CE Campiglio… - … journal of artificial …, 2018 - journals.sagepub.com
Advances in regenerative medicine and in modern biomedical therapies are fast evolving
and set goals causing an upheaval in the field of materials science. This review discusses …