Molecular probes, chemosensors, and nanosensors for optical detection of biorelevant molecules and ions in aqueous media and biofluids

J Krämer, R Kang, LM Grimm, L De Cola… - Chemical …, 2022 - ACS Publications
Synthetic molecular probes, chemosensors, and nanosensors used in combination with
innovative assay protocols hold great potential for the development of robust, low-cost, and …

Deuterium‐and tritium‐labelled compounds: applications in the life sciences

J Atzrodt, V Derdau, WJ Kerr… - Angewandte chemie …, 2018 - Wiley Online Library
Hydrogen isotopes are unique tools for identifying and understanding biological and
chemical processes. Hydrogen isotope labelling allows for the traceless and direct …

Aggregation-induced emission luminogen: role in biopsy for precision medicine

Y Duo, L Han, Y Yang, Z Wang, L Wang… - Chemical …, 2024 - ACS Publications
Biopsy, including tissue and liquid biopsy, offers comprehensive and real-time physiological
and pathological information for disease detection, diagnosis, and monitoring. Fluorescent …

Recent advances in LC‐MS‐based metabolomics for clinical biomarker discovery

CJ Chen, DY Lee, J Yu, YN Lin… - Mass spectrometry …, 2023 - Wiley Online Library
The employment of liquid chromatography‐mass spectrometry (LC‐MS) untargeted and
targeted metabolomics has led to the discovery of novel biomarkers and improved the …

Development and application of liquid chromatographic retention time indices in HRMS-based suspect and nontarget screening

R Aalizadeh, NA Alygizakis, EL Schymanski… - Analytical …, 2021 - ACS Publications
There is an increasing need for comparable and harmonized retention times (t R) in liquid
chromatography (LC) among different laboratories, to provide supplementary evidence for …

Metabolite measurement: pitfalls to avoid and practices to follow

W Lu, X Su, MS Klein, IA Lewis, O Fiehn… - Annual review of …, 2017 - annualreviews.org
Metabolites are the small biological molecules involved in energy conversion and
biosynthesis. Studying metabolism is inherently challenging due to metabolites' reactivity …

Metabolomic and immune alterations in long COVID patients with chronic fatigue syndrome

S Saito, S Shahbaz, X Luo, M Osman… - Frontiers in …, 2024 - frontiersin.org
Introduction A group of SARS-CoV-2 infected individuals present lingering symptoms,
defined as long COVID (LC), that may last months or years post the onset of acute disease …

[HTML][HTML] The human urine metabolome

S Bouatra, F Aziat, R Mandal, AC Guo, MR Wilson… - PloS one, 2013 - journals.plos.org
Urine has long been a “favored” biofluid among metabolomics researchers. It is sterile, easy-
to-obtain in large volumes, largely free from interfering proteins or lipids and chemically …

Recurrent topics in mass spectrometry-based metabolomics and lipidomics—standardization, coverage, and throughput

E Rampler, YE Abiead, H Schoeny, M Rusz… - Analytical …, 2020 - ACS Publications
We have come a long way in the last years of develo** analytical strategies in
metabolomics. We have seen huge progress in tackling multiplatform measurement, data …

Metabolite identification and quantitation in LC-MS/MS-based metabolomics

JF **ao, B Zhou, HW Ressom - TrAC Trends in Analytical Chemistry, 2012 - Elsevier
Metabolomics aims at detection and quantitation of all metabolites in biological samples.
The presence of metabolites with a wide variety of physicochemical properties and different …