Insulin is a polypeptide hormone mainly secreted by β cells in the islets of Langerhans of the
pancreas. The hormone potentially coordinates with glucagon to modulate blood glucose …

The ageing process is a systemic decline from cellular dysfunction to organ degeneration,
with more predisposition to deteriorated disorders. Rejuvenation refers to giving aged cells …

Skin is the outermost covering of the human body and at the same time the largest organ
comprising 15% of body weight and 2 m2 surface area. Skin plays a key role as a barrier …

The growing incidence of melanoma is a serious public health issue that merits a thorough
understanding of potential causative risk factors, which includes exposure to ultraviolet …

The circadian clock is an evolutionarily conserved timekeeper that adapts body physiology
to diurnal cycles of around 24 h by influencing a wide variety of processes such as sleep‐to …

For almost a quarter of a century, ex vivo studies of human scalp hair follicles (HF s) have
permitted major advances in hair research, spanning diverse fields such as chronobiology …

We live on a planet that is bathed in daily and seasonal sunlight cycles. In this context,
terrestrial life forms have evolved mechanisms that directly harness light energy (plants) or …

Skin is the largest organ in the body and serves important barrier, regulatory, and sensory
functions. The epidermal layer shows rhythmic physiological responses to daily …

Organisms have an evolutionarily conserved internal rhythm that helps them anticipate and
adapt to daily changes in the environment. Synchronized to the light–dark cycle with a …

Immune responses are gated to protect the host against specific antigens and microbes, a
task that is achieved through antigen-and pattern-specific receptors. Less appreciated is that …