Serotonin regulates many physiological processes including sleep, appetite, and mood.
Thus, serotonergic system is an important target in the treatment of psychiatric disorders …

Serotonin (5-hydroxytryptamine; 5-HT) is a monoamine neurotransmitter whose effects are
mediated by at least 13 distinct G protein-coupled receptors (GPCRs) of the type A family …

The 5-HT1A receptor is highly expressed both in 5-HT neurons as a presynaptic inhibitory
autoreceptor, and in many brain regions innervated by 5-HT as a post-synaptic …

The aim of this review is to provide a systematic overview on constitutively active G-protein-
coupled receptors (GPCRs), a rapidly evolving area in signal transduction research. We will …

The serotonin (5-hydroxytryptamine, 5-HT) receptors have been divided into 7 subfamilies
by convention, 6 of which include 13 different genes for G-protein-coupled receptors. Those …

Serotonin is a key neurotransmitter that is implicated in a wide variety of behavioral and
cognitive phenotypes. Originating in the raphe nuclei, 5-HT neurons project widely to …

Violence and aggression are major public health problems. 2. The authors have used
techniques of electrical brain stimulation, anatomical-immunohistochemical techniques, and …

Abstract Serotonin (5-hydroxytryptamine, 5-HT) is, without doubt, the neurotransmitter for
which the number of receptors is the highest. Fifteen genes encoding functional 5-HT …

The serotonin system is implicated in major depression and suicide and is negatively
regulated by somatodendritic 5-HT1A autoreceptors. Desensitization of 5-HT1A …

Abstract The neurotransmitter 5-hydroxytryptamine (5-HT), commonly known as serotonin, is
stored at peripheral sites in mast cells and released from this peripheral source upon IgE …