Aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that induces the
expression of a broad range of downstream genes such as cytochromes P450 enzymes and …

Increasing evidence on the significance of nutrition in reproduction is emerging from both
animal and human studies, suggesting a mutual association between nutrition and female …

Oxidative stress can affect the protein, lipids, and DNA of the cells and thus, play a crucial
role in several pathophysiological conditions. It has already been established that oxidative …

Tryptophan (TRP) is an essential dietary amino acid that, unless otherwise committed to
protein synthesis, undergoes metabolism via the Tryptophan-Kynurenine (TRP-KYN) …

Background Nuclear factor erythroid 2-related factor 2 (Nrf2) is a classical nuclear
transcription factor that regulates the system's anti-oxidative stress response. The activation …

As the COVID-19 pandemic intensified the global health crisis, the containment of SARS-
CoV-2 infection in pregnancies, and the inherent risk of vertical transmission of virus from …

Aims Epidemiological studies have correlated cardiovascular disease and atherosclerosis
with lifestyle factors such as sedentary behaviour and a high‐calorie diet. Recent studies of …

Background There is now evidence that affective disorders including major depressive
disorder (MDD) and bipolar disorder (BD) are mediated by immune-inflammatory and nitro …

(L-) tryptophan is metabolized via the kynurenine pathway into several kynurenine
metabolites with distinct functions. Dysfunction of the kynurenine pathway can lead to …

The intricate and dynamic tryptophan (Trp) metabolic pathway in both the microbiome and
host cells highlights its profound implications for health and disease. This pathway involves …