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A field guide to whole‐genome sequencing, assembly and annotation
Genome sequencing projects were long confined to biomedical model organisms and
required the concerted effort of large consortia. Rapid progress in high‐throughput …
required the concerted effort of large consortia. Rapid progress in high‐throughput …
Technology dictates algorithms: recent developments in read alignment
Aligning sequencing reads onto a reference is an essential step of the majority of genomic
analysis pipelines. Computational algorithms for read alignment have evolved in …
analysis pipelines. Computational algorithms for read alignment have evolved in …
Assembly of allele-aware, chromosomal-scale autopolyploid genomes based on Hi-C data
Construction of chromosome-level assembly is a vital step in achieving the goal of a
'Platinum'genome, but it remains a major challenge to assemble and anchor sequences to …
'Platinum'genome, but it remains a major challenge to assemble and anchor sequences to …
Genomes of 13 domesticated and wild rice relatives highlight genetic conservation, turnover and innovation across the genus Oryza
The genus Oryza is a model system for the study of molecular evolution over time scales
ranging from a few thousand to 15 million years. Using 13 reference genomes spanning the …
ranging from a few thousand to 15 million years. Using 13 reference genomes spanning the …
[HTML][HTML] 1,135 genomes reveal the global pattern of polymorphism in Arabidopsis thaliana
Arabidopsis thaliana serves as a model organism for the study of fundamental physiological,
cellular, and molecular processes. It has also greatly advanced our understanding of …
cellular, and molecular processes. It has also greatly advanced our understanding of …
The pangenome of an agronomically important crop plant Brassica oleracea
There is an increasing awareness that as a result of structural variation, a reference
sequence representing a genome of a single individual is unable to capture all of the gene …
sequence representing a genome of a single individual is unable to capture all of the gene …
Origin and evolution of the triploid cultivated banana genome
X Li, S Yu, Z Cheng, X Chang, Y Yun, M Jiang… - Nature …, 2024 - nature.com
Most fresh bananas belong to the Cavendish and Gros Michel subgroups. Here, we report
chromosome-scale genome assemblies of Cavendish (1.48 Gb) and Gros Michel (1.33 Gb) …
chromosome-scale genome assemblies of Cavendish (1.48 Gb) and Gros Michel (1.33 Gb) …
A map of rice genome variation reveals the origin of cultivated rice
X Huang, N Kurata, X Wei, ZX Wang, A Wang, Q Zhao… - Nature, 2012 - nature.com
Crop domestications are long-term selection experiments that have greatly advanced
human civilization. The domestication of cultivated rice (Oryza sativa L.) ranks as one of the …
human civilization. The domestication of cultivated rice (Oryza sativa L.) ranks as one of the …
Chromosome-level assemblies of multiple Arabidopsis genomes reveal hotspots of rearrangements with altered evolutionary dynamics
Despite hundreds of sequenced Arabidopsis genomes, very little is known about the degree
of genomic collinearity within single species, due to the low number of chromosome-level …
of genomic collinearity within single species, due to the low number of chromosome-level …
High contiguity Arabidopsis thaliana genome assembly with a single nanopore flow cell
Abstract The handheld Oxford Nanopore MinION sequencer generates ultra-long reads with
minimal cost and time requirements, which makes sequencing genomes at the bench …
minimal cost and time requirements, which makes sequencing genomes at the bench …